Table 3.

Distribution of HLA class II DRB1* and DQB1* subtypes in homozygotes for type II mutation with and without an inhibitor to factor XI

Patients with an inhibitor, N = 10
Patients without an inhibitor, N = 13
HLA type
No.
%
No.
%
P
DRB1*01   1   10   2   15   1.00  
DRB1*03   1   10   2   15   1.00  
DRB1*04   6   60   5   38   0.41  
DRB1*0701   5   50   2   15   0.17  
DRB1*11   4   40   7   54   0.68  
DRB1*12   1   10   1   8   1.00  
DRB1*13   1   10   5   38   0.18  
DRB1*14   1   10   0   0   0.43  
DRB1*15   0   0   1   8   1.00  
DRB1*16   0   0   1   8   1.00  
DRB1*02   6   60   4   31   0.22  
DRB1*03   10*  100   11†  85   0.49  
DRB1*05   2   20   3   23   1.00  
DRB1*06
 		 1
 		 10
 		 6
 		 46
 		 0.09
 
Patients with an inhibitor, N = 10
Patients without an inhibitor, N = 13
HLA type
No.
%
No.
%
P
DRB1*01   1   10   2   15   1.00  
DRB1*03   1   10   2   15   1.00  
DRB1*04   6   60   5   38   0.41  
DRB1*0701   5   50   2   15   0.17  
DRB1*11   4   40   7   54   0.68  
DRB1*12   1   10   1   8   1.00  
DRB1*13   1   10   5   38   0.18  
DRB1*14   1   10   0   0   0.43  
DRB1*15   0   0   1   8   1.00  
DRB1*16   0   0   1   8   1.00  
DRB1*02   6   60   4   31   0.22  
DRB1*03   10*  100   11†  85   0.49  
DRB1*05   2   20   3   23   1.00  
DRB1*06
 		 1
 		 10
 		 6
 		 46
 		 0.09
 

All patients were exposed to plasma products.

*

One patient was homozygous for this allele.

†

Two patients were homozygous for this allele.

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