Patient characteristics
Parameter . | No. of patients . |
|---|---|
| Sex | |
| Male | 32 |
| Female | 29 |
| Median age, y (range) | 38 (16-55) |
| Diagnostic indication for SCT | |
| Acute myelogenous leukemia | 17 |
| Acute lymphoblastic leukemia | 10 |
| Myelodysplastic syndrome | 1 |
| Chronic myeloid leukemia | 8 |
| Non-Hodgkin lymphoma | 16 |
| Multiple myeloma | 8 |
| Severe aplastic anemia | 1 |
| Stem cell donor type | |
| HLA-matched related donor | 39 |
| HLA-matched unrelated donor | 22 |
| Conditioning regimen | |
| Cy + TBI | 35 |
| Cy + TBI + ATG | 23 |
| Bu + Cy | 3 |
| Stem cell source | |
| Bone marrow | 51 |
| Mobilized peripheral blood | 10 |
| Graft characteristics, median (range) | |
| CD34+ hematopoietic stem cells, × 106/kg | 1.6 (0.5-8.8) |
| CD3+T lymphocytes, × 105/kg | 2.0 (1.0-7.5) |
| EBV serology prior to SCT | |
| Recipient positive, SCT donor positive | 55 |
| Recipient positive, SCT donor negative | 3 |
| Recipient negative, SCT donor positive | 3 |
| Recipient negative, SCT donor negative | 0 |
Parameter . | No. of patients . |
|---|---|
| Sex | |
| Male | 32 |
| Female | 29 |
| Median age, y (range) | 38 (16-55) |
| Diagnostic indication for SCT | |
| Acute myelogenous leukemia | 17 |
| Acute lymphoblastic leukemia | 10 |
| Myelodysplastic syndrome | 1 |
| Chronic myeloid leukemia | 8 |
| Non-Hodgkin lymphoma | 16 |
| Multiple myeloma | 8 |
| Severe aplastic anemia | 1 |
| Stem cell donor type | |
| HLA-matched related donor | 39 |
| HLA-matched unrelated donor | 22 |
| Conditioning regimen | |
| Cy + TBI | 35 |
| Cy + TBI + ATG | 23 |
| Bu + Cy | 3 |
| Stem cell source | |
| Bone marrow | 51 |
| Mobilized peripheral blood | 10 |
| Graft characteristics, median (range) | |
| CD34+ hematopoietic stem cells, × 106/kg | 1.6 (0.5-8.8) |
| CD3+T lymphocytes, × 105/kg | 2.0 (1.0-7.5) |
| EBV serology prior to SCT | |
| Recipient positive, SCT donor positive | 55 |
| Recipient positive, SCT donor negative | 3 |
| Recipient negative, SCT donor positive | 3 |
| Recipient negative, SCT donor negative | 0 |
SCT indicates stem cell transplantation; HLA, human leukocyte antigen; Cy, cyclophosphamide; TBI, total body irradiation; ATG, antithymocyte globulin; Bu, busulfan; and EBV, Epstein-Barr virus.