Table 3. Selected coagulation and... | American Society of Hematology

Table 3.

Selected coagulation and clinical chemistry data

	Age, months	Fibrinogen level, g/L	Prothrombin time, s	Total bilirubin level, μM	Potassium level, mM	Free hemoglobin level, mg/L
Wild-type
	1	ND	ND	ND	ND	879.5 ± 303.3
	2	1.7 ± 0.9	11.8 ± 0.9	<2	4.2 ± 1.1	747.7 ± 778.6
	4	1.3 ± 0.4	11.6 ± 0.9	<2	4.3 ± 1.5	633.8 ± 339.8
	6	1.5 ± 0.7	12.0 ± 1.1	<2	4.5 ± 1.2	199.3 ± 96.4
	8	1.4 ± 0.5	11.6 ± 0.9	<2	4.7 ± 1.8	395.8 ± 182.5
Transgenic
	1	ND	ND	<2	ND	1531.3 ± 1025.4
	2	1.5 ± 0.7	16.6 ± 0.7*	<2	5.3 ± 0.8	1794.6 ± 1506.6
	4	1.7 ± 1.1	17.5 ± 1.7*	<2	5.1 ± 1.3	9000.0 ± 2642.0*
	6	1.5 ± 0.7	17.1 ± 0.9*	<2	4.8 ± 1.2	3317.5 ± 62.9*
	8	1.3 ± 0.8	17.6 ± 2.3*	4.5 ± 2.2	4.3 ± 1.2	5613.3 ± 3940.8†

	Age, months	Fibrinogen level, g/L	Prothrombin time, s	Total bilirubin level, μM	Potassium level, mM	Free hemoglobin level, mg/L
Wild-type
	1	ND	ND	ND	ND	879.5 ± 303.3
	2	1.7 ± 0.9	11.8 ± 0.9	<2	4.2 ± 1.1	747.7 ± 778.6
	4	1.3 ± 0.4	11.6 ± 0.9	<2	4.3 ± 1.5	633.8 ± 339.8
	6	1.5 ± 0.7	12.0 ± 1.1	<2	4.5 ± 1.2	199.3 ± 96.4
	8	1.4 ± 0.5	11.6 ± 0.9	<2	4.7 ± 1.8	395.8 ± 182.5
Transgenic
	1	ND	ND	<2	ND	1531.3 ± 1025.4
	2	1.5 ± 0.7	16.6 ± 0.7*	<2	5.3 ± 0.8	1794.6 ± 1506.6
	4	1.7 ± 1.1	17.5 ± 1.7*	<2	5.1 ± 1.3	9000.0 ± 2642.0*
	6	1.5 ± 0.7	17.1 ± 0.9*	<2	4.8 ± 1.2	3317.5 ± 62.9*
	8	1.3 ± 0.8	17.6 ± 2.3*	4.5 ± 2.2	4.3 ± 1.2	5613.3 ± 3940.8†

Time course of some coagulation and clinical chemistry data of transgenic animals and age-matched controls; n = 3 to 6 per group.

ND indicates not determined.

P < 0.01.

P < 0.001 for age-matched intergroup comparison.