Thrombin and fibrin generation
. | Thrombin generation, pmol/s . | Fibrin molecules produced per thrombin* . | Percent total fibrin formed as soluble fibrin† . |
|---|---|---|---|
| Baseline | 0.24 ± 0.11 | 108 ± 133 | 1 ± 1 |
| CPB, 5 min | 5.60 ± 6.65‡ | 4 ± 3‡ | 35 ± 34‡ |
| CPB, 30 min | 2.13 ± 2.00 | 8 ± 6‡ | 4 ± 4 |
| Reperfusion | 5.47 ± 4.08‡ | 5 ± 7‡ | 10 ± 11‡ |
| 2 h after surgery | 1.90 ± 1.60 | 17 ± 16‡ | 3 ± 3 |
. | Thrombin generation, pmol/s . | Fibrin molecules produced per thrombin* . | Percent total fibrin formed as soluble fibrin† . |
|---|---|---|---|
| Baseline | 0.24 ± 0.11 | 108 ± 133 | 1 ± 1 |
| CPB, 5 min | 5.60 ± 6.65‡ | 4 ± 3‡ | 35 ± 34‡ |
| CPB, 30 min | 2.13 ± 2.00 | 8 ± 6‡ | 4 ± 4 |
| Reperfusion | 5.47 ± 4.08‡ | 5 ± 7‡ | 10 ± 11‡ |
| 2 h after surgery | 1.90 ± 1.60 | 17 ± 16‡ | 3 ± 3 |
Ratio of total fibrin generation rate to thrombin generation rate, number of total fibrin molecules produced for each new thrombin formed.
Ratio of soluble fibrin generation rate to total fibrin generation rate, percent of total fibrin generated in the form of soluble fibrin.
P < .001 compared with baseline.