Table 4. Outcomes for 17 sibling cord... | American Society of Hematology

Table 4.

Outcomes for 17 sibling cord blood units released from CHORI Sibling Donor Cord Blood Program and transplanted

Recipient	Disease	Age, y	Cell dose, TNC/kg × 10⁷	HLA match	Time to engraftment, d		Follow-up, mo
Recipient	Disease	Age, y	Cell dose, TNC/kg × 10⁷	HLA match	Neutrophils	Platelets	Follow-up, mo
1	SCA	2.0	9.15	6/6	20	43	25.4
2	SCA	9.5	5.77	6/6	30	70	22.3
3	SCA	13.6	1.67	6/6	13	24	—^4-153
4	SCA	7.1	3.12	6/6	45	46	5.2
5	Thal	4.4	4.18	6/6	16	20	41.8
6	Thal	2.4	6.92	6/6	40	75	35.7
7	Thal	4.3	7.86	6/6	24	60	21.7
8	Thal	6.5	7.22	6/6	34	29	18.0
9	Thal	2.8	4.81	6/6	25	57	15.2
10	Thal	2.4	12.45	6/6	28	45	1.4
11	Thal	6.9	3.97	6/6	18	39	4.1
12	SAA	3.2	1.36	4/6	38	138	47.3
13	SAA	13.0	1.78	6/6	22	34	15.0
14	MD	6.8	8.22	6/6	40	51	30.9
15	AML	2.6	7.54	4/6	D^4-155	D^4-155	D^4-154
16	ALL	6.3	3.53	6/6	45	73	6.5
17	ALL	5.2	2.22	3/6	50	P	2.9

Recipient	Disease	Age, y	Cell dose, TNC/kg × 10⁷	HLA match	Time to engraftment, d		Follow-up, mo
Recipient	Disease	Age, y	Cell dose, TNC/kg × 10⁷	HLA match	Neutrophils	Platelets	Follow-up, mo
1	SCA	2.0	9.15	6/6	20	43	25.4
2	SCA	9.5	5.77	6/6	30	70	22.3
3	SCA	13.6	1.67	6/6	13	24	—^4-153
4	SCA	7.1	3.12	6/6	45	46	5.2
5	Thal	4.4	4.18	6/6	16	20	41.8
6	Thal	2.4	6.92	6/6	40	75	35.7
7	Thal	4.3	7.86	6/6	24	60	21.7
8	Thal	6.5	7.22	6/6	34	29	18.0
9	Thal	2.8	4.81	6/6	25	57	15.2
10	Thal	2.4	12.45	6/6	28	45	1.4
11	Thal	6.9	3.97	6/6	18	39	4.1
12	SAA	3.2	1.36	4/6	38	138	47.3
13	SAA	13.0	1.78	6/6	22	34	15.0
14	MD	6.8	8.22	6/6	40	51	30.9
15	AML	2.6	7.54	4/6	D^4-155	D^4-155	D^4-154
16	ALL	6.3	3.53	6/6	45	73	6.5
17	ALL	5.2	2.22	3/6	50	P	2.9

Except for 3 and 15, all recipients were in continuous remission at the time of writing.

SCA indicates sickle cell anemia; Thal, thalassemia major; SAA, severe aplastic anemia; MD, myelodysplasia; AML, acute myeloid leukemia; ALL, acute lymphoblastic leukemia; D, deceased; and P, pending.

F4-150

These recipients received CBUs combined with marrow from the same sibling donor.

F4-151

These recipients received reduced-intensity conditioning to induce mixed chimerism.

‡

This recipient was given a supplemental infusion of peripheral blood stem cells at day 55.

F4-153

This recipient died at day 80 after transplantation.

F4-155

This recipient had primary engraftment failure.

F4-154

This recipient died at 3.7 months after transplantation.

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