Postprocessing laboratory characteristics of banked and unbanked sibling cord blood units
| . | Banked . | Unbanked . |
|---|---|---|
| Volume, mean (SD; range), mL* | 103.1 (32.7; 42-256) | 42.3 (8.2; 35-65) |
| Total nucleated cells, mean (SD; range)† | 8.9 × 108 (6.0; 0.6-36.2) | 1.1 × 108 (0.8; 0.2-2.6) |
| Total mononuclear cells, mean (SD; range)† | 4.9 × 108 (3.6; 0.3-27.2) | ND |
| Total CD34+ cells, mean (SD; range) | 2.1 × 106 (2.4; 0.1-21.2) | ND |
| Total CFUs, mean (SD; range)† | 1.4 × 106 (1.6; 0.04-13.5) | ND |
| Nucleated cell recovery, mean (SD; range), %‡ | 84.4 (9.2; 41.7-98.4) | ND |
| . | Banked . | Unbanked . |
|---|---|---|
| Volume, mean (SD; range), mL* | 103.1 (32.7; 42-256) | 42.3 (8.2; 35-65) |
| Total nucleated cells, mean (SD; range)† | 8.9 × 108 (6.0; 0.6-36.2) | 1.1 × 108 (0.8; 0.2-2.6) |
| Total mononuclear cells, mean (SD; range)† | 4.9 × 108 (3.6; 0.3-27.2) | ND |
| Total CD34+ cells, mean (SD; range) | 2.1 × 106 (2.4; 0.1-21.2) | ND |
| Total CFUs, mean (SD; range)† | 1.4 × 106 (1.6; 0.04-13.5) | ND |
| Nucleated cell recovery, mean (SD; range), %‡ | 84.4 (9.2; 41.7-98.4) | ND |
Of the banked CBUs, 18 (3.5%) of 506 failed the sterility test, and 18 (4.7%) of 384 showed clinically significant hemoglobinopathy. Of the 540 mothers, 55 (10.2%) showed a repeat reactive infectious marker (non-CMV; 1 HBV sAg, 2 HCV, 2 p24Ag, 3 HTLV, 8 RPR, 39 anti-HBC).
ND indicates not done.
Including anticoagulant.
Postprocessing values.
Recovery was determined by dividing postprocessing TNC count by preprocessing TNC count, starting with CBU 317; therefore, n = 233.