Tetramers used for this study
| Virus . | Protein . | Amino acids . | Sequence . | Restricting element . | %tetramer-positive CD8 T cells [median, (range)] . | Reference . | |
|---|---|---|---|---|---|---|---|
| Healthy donor . | HIV seropositive . | ||||||
| HIV | gag | 77-85 | SLYNTVATL | A0201 | — | 0.53 (0.14, 1.85) | 22-24 |
| HIV | RT | 309-317 | ILKEPVHGV | A0201 | — | 0.49 (0.27, 0.95) | 22,24,25 |
| HIV | RT | 293-302 | KYTAFTIPSI | A0201 | — | 0.64 (0.60, 0.81) | 26 |
| HIV | env | 593-600 | YLKDQQLL | B8 | — | 0.11 (0.05, 0.13) | 27 |
| CMV | pp65 | 495-503 | NLVPMVATV | A0201 | 0.48 (0.25, 4.24) | 1.89 (0.30, 11.0) | 28-30 |
| EBV | BMLF1 | 280-288 | GLCTLVAML | A0201 | 0.15 (0.08, 0.43) | 0.46 (0.16, 2.23) | 31,32 |
| EBV | BZLF1 | 190-197 | RAKFKQLL | B8 | 0.74 (0.37, 1.02) | 1.04 (0.18, 3.46) | 31,32 |
| Virus . | Protein . | Amino acids . | Sequence . | Restricting element . | %tetramer-positive CD8 T cells [median, (range)] . | Reference . | |
|---|---|---|---|---|---|---|---|
| Healthy donor . | HIV seropositive . | ||||||
| HIV | gag | 77-85 | SLYNTVATL | A0201 | — | 0.53 (0.14, 1.85) | 22-24 |
| HIV | RT | 309-317 | ILKEPVHGV | A0201 | — | 0.49 (0.27, 0.95) | 22,24,25 |
| HIV | RT | 293-302 | KYTAFTIPSI | A0201 | — | 0.64 (0.60, 0.81) | 26 |
| HIV | env | 593-600 | YLKDQQLL | B8 | — | 0.11 (0.05, 0.13) | 27 |
| CMV | pp65 | 495-503 | NLVPMVATV | A0201 | 0.48 (0.25, 4.24) | 1.89 (0.30, 11.0) | 28-30 |
| EBV | BMLF1 | 280-288 | GLCTLVAML | A0201 | 0.15 (0.08, 0.43) | 0.46 (0.16, 2.23) | 31,32 |
| EBV | BZLF1 | 190-197 | RAKFKQLL | B8 | 0.74 (0.37, 1.02) | 1.04 (0.18, 3.46) | 31,32 |