Distribution of absorbed 59Fe and percentage transferrin saturation in mice maintained on control or 2% carbonyl iron–supplemented diets
Strain . | Diet . | Blood, % . | Liver, % . | % Tf saturation . |
---|---|---|---|---|
+/+ (n = 5) | Control | 33.5 ± 4.5 | 8.8 ± 0.8 | 48.0 ± 1.7 |
+/+ (n = 8) | High Fe | 20.1 ± 5.0 | 36.0 ± 9.8* | 59.8 ± 7.0 |
−/− (n = 6) | Control | 18.7 ± 3.7 | 43.7 ± 5.5 | 81.0 ± 5.0 |
−/− (n = 7) | High Fe | 7.0 ± 0.9* | 67.8 ± 1.6* | 89.0 ± 4.7 |
Y/Y (n = 9) | Control | 30.0 ± 3.0 | 29.0 ± 5.5 | 86.1 ± 2.7 |
Y/Y (n = 8) | High Fe | 16.7 ± 2.2* | 46.8 ± 4.6* | 92 ± 3.4 |
Strain . | Diet . | Blood, % . | Liver, % . | % Tf saturation . |
---|---|---|---|---|
+/+ (n = 5) | Control | 33.5 ± 4.5 | 8.8 ± 0.8 | 48.0 ± 1.7 |
+/+ (n = 8) | High Fe | 20.1 ± 5.0 | 36.0 ± 9.8* | 59.8 ± 7.0 |
−/− (n = 6) | Control | 18.7 ± 3.7 | 43.7 ± 5.5 | 81.0 ± 5.0 |
−/− (n = 7) | High Fe | 7.0 ± 0.9* | 67.8 ± 1.6* | 89.0 ± 4.7 |
Y/Y (n = 9) | Control | 30.0 ± 3.0 | 29.0 ± 5.5 | 86.1 ± 2.7 |
Y/Y (n = 8) | High Fe | 16.7 ± 2.2* | 46.8 ± 4.6* | 92 ± 3.4 |
Mouse strains are explained in Table 1. Error presented as SEM.
Values for control vs high Fe diet, P < .05. Percentages represent the percentage of absorbed radioiron.