Sites of posttranslational modifications of the factor V molecule
| Phosphorylation | Ser692, Ser804, Ser1506 for platelet casein kinase II; at least 2 sites for protein kinase C on the light chain |
| Sulfation | Tyr665, Tyr696, Tyr698, Tyr1494, Tyr1510, Tyr1515, Tyr1565 |
| N-glycosylation | |
| Heavy chain | Asn23, Asn27, Asn211, Asn269, Asn354, Asn432, Asn440, Asn526, Asn639 |
| B region | Asn713, Asn724, Asn732, Asn748, Asn754, Asn793, Asn910, Asn949, Asn1046, Asn1055, Asn1075, Asn1078, Asn1175, Asn1193, Asn1229, Asn1238, Asn1265, Asn1283, Asn1310, Asn1319, Asn1347, Asn1356, Asn1451, Asn1471, Asn1531 |
| Light chain | Asn1675, Asn1982, Asn2182 |
| Disulfide bridges | |
| Heavy chain | Cys139-Cys165, Cys220-Cys301, Cys472-Cys498, Cys575-Cys656 |
| B region | No disulfides |
| Light chain | Cys1697-Cys1723, Cys1879-Cys2033, Cys2038-Cys2193 |
| Free cysteines | |
| Heavy chain | Cys539, Cys585 |
| B region | Cys1085 |
| Light chain | Cys1960, Cys2113 |
| Phosphorylation | Ser692, Ser804, Ser1506 for platelet casein kinase II; at least 2 sites for protein kinase C on the light chain |
| Sulfation | Tyr665, Tyr696, Tyr698, Tyr1494, Tyr1510, Tyr1515, Tyr1565 |
| N-glycosylation | |
| Heavy chain | Asn23, Asn27, Asn211, Asn269, Asn354, Asn432, Asn440, Asn526, Asn639 |
| B region | Asn713, Asn724, Asn732, Asn748, Asn754, Asn793, Asn910, Asn949, Asn1046, Asn1055, Asn1075, Asn1078, Asn1175, Asn1193, Asn1229, Asn1238, Asn1265, Asn1283, Asn1310, Asn1319, Asn1347, Asn1356, Asn1451, Asn1471, Asn1531 |
| Light chain | Asn1675, Asn1982, Asn2182 |
| Disulfide bridges | |
| Heavy chain | Cys139-Cys165, Cys220-Cys301, Cys472-Cys498, Cys575-Cys656 |
| B region | No disulfides |
| Light chain | Cys1697-Cys1723, Cys1879-Cys2033, Cys2038-Cys2193 |
| Free cysteines | |
| Heavy chain | Cys539, Cys585 |
| B region | Cys1085 |
| Light chain | Cys1960, Cys2113 |
See also Figure 1A for the positions.