Table 1. Clinical characteristics of 12... | American Society of Hematology

Table 1.

Clinical characteristics of 12 patients at start of iron chelation

Patient no.	Diagnosis	Sex	Age, y	Liver iron, μM/g	Ferritin, μg/L	TfS, %	Blood transfusions
Patient no.	Diagnosis	Sex	Age, y	Liver iron, μM/g	Ferritin, μg/L	TfS, %	U^*	U/mo
1	MDS, RARS	M	58	501	3600	88	132	8.1
2	MDS, RA	F	67	521	4340	79	77	3.8
3	MDS, RA	F	32	405	1740	84	44	3.0
4	MDS, RAEB	F	63	558	1780	94	116	4.7
5	MDS, RA+ERD	F	47	403	2510	75	105	4.8
6	MDS, RA	F	64	540	5770	83	88	5.7
7	MDS, RA	F	46	558	3800	88	75	3.2
8	MDS, RA	F	41	623	8715	100	254	2.9
9^†	DBS	M	37	388	2380	108	420	3.1
10	AML, CR	M	34	468	2200	62	109	3.0
11	CH	F	41	479	1280	66	70	1.0
12	MDS, RARS	M	69	491	4790	102	90	4.0

Patient no.	Diagnosis	Sex	Age, y	Liver iron, μM/g	Ferritin, μg/L	TfS, %	Blood transfusions
Patient no.	Diagnosis	Sex	Age, y	Liver iron, μM/g	Ferritin, μg/L	TfS, %	U^*	U/mo
1	MDS, RARS	M	58	501	3600	88	132	8.1
2	MDS, RA	F	67	521	4340	79	77	3.8
3	MDS, RA	F	32	405	1740	84	44	3.0
4	MDS, RAEB	F	63	558	1780	94	116	4.7
5	MDS, RA+ERD	F	47	403	2510	75	105	4.8
6	MDS, RA	F	64	540	5770	83	88	5.7
7	MDS, RA	F	46	558	3800	88	75	3.2
8	MDS, RA	F	41	623	8715	100	254	2.9
9^†	DBS	M	37	388	2380	108	420	3.1
10	AML, CR	M	34	468	2200	62	109	3.0
11	CH	F	41	479	1280	66	70	1.0
12	MDS, RARS	M	69	491	4790	102	90	4.0

TfS indicates iron saturation of serum transferrin; MDS, myelodysplastic syndromes (classified according to French-American-British criteria); RARS, refractory anemia with ringed sideroblasts; RA, refractory anemia; RAEB, refractory anemia with excess of blasts; ERD, end-stage renal disease; DBS, Diamond-Blackfan syndrome; AML CR, acute myeloid leukemia in complete remission; and CH, chronic hemolysis of unknown etiology.

Total number of transfused blood units.

†

Patient 9 had been on iron chelation for 9 months when entering the study.

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