Maximum toxicity during induction by regimen
| Toxicity by treatment type . | Toxicity grade, % . | |||
|---|---|---|---|---|
| Grade 1 . | Grade 2 . | Grade 3 . | Grade 4 . | |
| Neutropenia | ||||
| Concurrent | 2 | 6 | 33 | 43 |
| Sequential | 21 | 21 | 11 | 28 |
| Thrombocytopenia | ||||
| Concurrent | 33 | 14 | 14 | 6 |
| Sequential | 36 | 13 | 8 | 2 |
| Anemia | ||||
| Concurrent | 47 | 18 | 4 | 0 |
| Sequential | 45 | 15 | 0 | 0 |
| Infection | ||||
| Concurrent | 16 | 27 | 20 | 0 |
| Sequential | 17 | 32 | 21 | 2 |
| Nausea | ||||
| Concurrent | 38 | 10 | 0 | 0 |
| Sequential | 35 | 0 | 2 | 0 |
| Vomiting | ||||
| Concurrent | 8 | 8 | 0 | 0 |
| Sequential | 6 | 0 | 0 | 0 |
| Dyspnea | ||||
| Concurrent | 6 | 6 | 10 | 4 |
| Sequential | 2 | 4 | 6 | 0 |
| Hypotension | ||||
| Concurrent | 2 | 8 | 6 | 0 |
| Sequential | 2 | 2 | 0 | 0 |
| Fever | ||||
| Concurrent | 14 | 18 | 0 | 0 |
| Sequential | 4 | 14 | 0 | 0 |
| Chills | ||||
| Concurrent | 28 | 8 | 0 | 0 |
| Sequential | 6 | 2 | 0 | 0 |
| Myalgias | ||||
| Concurrent | 22 | 6 | 0 | 0 |
| Sequential | 8 | 0 | 0 | 0 |
| Fatigue/malaise | ||||
| Concurrent | 48 | 14 | 0 | 0 |
| Sequential | 36 | 22 | 4 | 0 |
| Toxicity by treatment type . | Toxicity grade, % . | |||
|---|---|---|---|---|
| Grade 1 . | Grade 2 . | Grade 3 . | Grade 4 . | |
| Neutropenia | ||||
| Concurrent | 2 | 6 | 33 | 43 |
| Sequential | 21 | 21 | 11 | 28 |
| Thrombocytopenia | ||||
| Concurrent | 33 | 14 | 14 | 6 |
| Sequential | 36 | 13 | 8 | 2 |
| Anemia | ||||
| Concurrent | 47 | 18 | 4 | 0 |
| Sequential | 45 | 15 | 0 | 0 |
| Infection | ||||
| Concurrent | 16 | 27 | 20 | 0 |
| Sequential | 17 | 32 | 21 | 2 |
| Nausea | ||||
| Concurrent | 38 | 10 | 0 | 0 |
| Sequential | 35 | 0 | 2 | 0 |
| Vomiting | ||||
| Concurrent | 8 | 8 | 0 | 0 |
| Sequential | 6 | 0 | 0 | 0 |
| Dyspnea | ||||
| Concurrent | 6 | 6 | 10 | 4 |
| Sequential | 2 | 4 | 6 | 0 |
| Hypotension | ||||
| Concurrent | 2 | 8 | 6 | 0 |
| Sequential | 2 | 2 | 0 | 0 |
| Fever | ||||
| Concurrent | 14 | 18 | 0 | 0 |
| Sequential | 4 | 14 | 0 | 0 |
| Chills | ||||
| Concurrent | 28 | 8 | 0 | 0 |
| Sequential | 6 | 2 | 0 | 0 |
| Myalgias | ||||
| Concurrent | 22 | 6 | 0 | 0 |
| Sequential | 8 | 0 | 0 | 0 |
| Fatigue/malaise | ||||
| Concurrent | 48 | 14 | 0 | 0 |
| Sequential | 36 | 22 | 4 | 0 |