Frequency of BCL-2/JHtranslocation in peripheral blood lymphocytes from males working at a nuclear power plant and from age-matched healthy male volunteers
| Group . | n . | t(14;18)-positive/total number tested (%) . | Multiple translocations/positive individuals (%) . |
|---|---|---|---|
| NPP (all) | 131 | 79/131* (60.3) | 27/79‡ (34.2) |
| NPP—A (less than 50 mSv) | 61 | 36/61† (59.0) | 16/36 (44.4) |
| NPP—B (50-100 mSV) | 34 | 21/34† (61.8) | 6/21 (28.6) |
| NPP—C (100-200 mSv) | 24 | 14/24† (58.3) | 1/14 (7.1) |
| NPP—D (200-400 mSv) | 12 | 8/12† (66.6) | 4/8 (50.0) |
| HV (all) | 131 | 72/131* (55.0) | 27/72‡ (37.5) |
| HV—A | 61 | 32/61† (52.5) | 15/32 (46.8) |
| HV—B | 34 | 16/34† (47.1) | 3/16 (18.8) |
| HV—C | 24 | 14/24† (58.3) | 5/14 (35.7) |
| HV—D | 12 | 10/12† (83.3) | 4/12 (33.3) |
| All | 262 | 151/262 (57.6) | 54/151 (35.8) |
| Group . | n . | t(14;18)-positive/total number tested (%) . | Multiple translocations/positive individuals (%) . |
|---|---|---|---|
| NPP (all) | 131 | 79/131* (60.3) | 27/79‡ (34.2) |
| NPP—A (less than 50 mSv) | 61 | 36/61† (59.0) | 16/36 (44.4) |
| NPP—B (50-100 mSV) | 34 | 21/34† (61.8) | 6/21 (28.6) |
| NPP—C (100-200 mSv) | 24 | 14/24† (58.3) | 1/14 (7.1) |
| NPP—D (200-400 mSv) | 12 | 8/12† (66.6) | 4/8 (50.0) |
| HV (all) | 131 | 72/131* (55.0) | 27/72‡ (37.5) |
| HV—A | 61 | 32/61† (52.5) | 15/32 (46.8) |
| HV—B | 34 | 16/34† (47.1) | 3/16 (18.8) |
| HV—C | 24 | 14/24† (58.3) | 5/14 (35.7) |
| HV—D | 12 | 10/12† (83.3) | 4/12 (33.3) |
| All | 262 | 151/262 (57.6) | 54/151 (35.8) |
NPP workers were separated into 4 groups based on their cumulative radiation exposure (50 to 400 mSv). The statistical analyses between the different groups were performed using the χ2-test.
NPP indicates male nuclear power plant workers; HV, age-matched healthy male volunteers.
These values represent the number of samples giving positive PCR results/the total number of samples in the group of NPP workers and healthy controls (χ2-test: P = .38).
These values represent the number of samples showing positive PCR results/the numbers of samples in subgroups A-D of NPP workers and healthy controls (χ2-test: A,P = .46; B, P = .22; C,P = 1.0; D, P = .35).
These values represent the number of samples with multiple translocations/the numbers of positive individuals in the group of NPP workers and healthy controls (χ2-test: all individuals in each group: P = 0.67; in subgroups: A,P = .84; B, P = .49; C,P = .065; D, P = .67).