Median duration of grade 3 and 4 hematologic toxicity during treatment period
| . | Baseline . | Nadir . | Days from baseline to nadir . | Median duration (d) . | |
|---|---|---|---|---|---|
| Method A . | Method B . | ||||
| ANC × 109/L | 2.8 | 0.6 | 68 | 28.5 | 15 |
| Platelets × 109/L | 127.5 | 26.5 | 56 | 29.5 | 16 |
| Hemoglobin g/dL | 12.1 | 10.1 | 69 | 12.5 | 4 |
| . | Baseline . | Nadir . | Days from baseline to nadir . | Median duration (d) . | |
|---|---|---|---|---|---|
| Method A . | Method B . | ||||
| ANC × 109/L | 2.8 | 0.6 | 68 | 28.5 | 15 |
| Platelets × 109/L | 127.5 | 26.5 | 56 | 29.5 | 16 |
| Hemoglobin g/dL | 12.1 | 10.1 | 69 | 12.5 | 4 |
ANC (absolute neutrophil count) < 1.0 × 109cells/L; platelets < 50 × 109 platelets/L; and hemoglobin < 8 g/dL; Method A, duration measured from last date in grade 2 before nadir to first date in grade 2 after nadir; method B, duration measured from first date in grade 3 before nadir to last date in grade 3 after nadir.