Table 2. Hematologic parameters of... | American Society of Hematology

Table 2.

Hematologic parameters of age-matched wild-type and GATA-1^low mice

	Age, mo
	4-8		8-12		15-20
	Wild type	GATA-1^low	Wild type	GATA-1^low	Wild type	GATA-1^low
Hct, %	50.1 ± 3.9	47.2 ± 2.3	48.5 ± 3.4	45.9 ± 4.0	45.3 ± 3.1	39.0 ± 3.9^*
Platelet count, × 10⁹/L	728.0 ± 135.0	118.0 ± 45.0^†	1300.0 ± 270.0	113.0 ± 35.0^†	1,060 ± 189.0	103.0 ± 45.0^†
White cell count, × 10⁹/L	8.1 ± 4.3	4.5 ± 2.8	5.0 ± 1.6	8.0 ± 2.5	6.7 ± 2.3	7.2 ± 1.1
Differential counts, %
Neutrophils	18.0 ± 5.0	25.0 ± 5.0	32.0 ± 12.0	54.0 ± 18.0	39.0 ± 9.0	64.0 ± 5.0^*
Lymphocytes	74.0 ± 12.0	63.0 ± 13.0	60.0 ± 9.0	36.0 ± 11.0	52.0 ± 7.0	22.0 ± 5.0^†
Monocytes	5.0 ± 3.0	10.0 ± 5.0	4.0 ± 2.0	6.0 ± 3.0	5.0 ± 2.0	6.0 ± 1.0
Eosinophils	3.0 ± 2.0	2.0 ± 1.0	2.0 ± 2.0	3.0 ± 2.0	3.0 ± 2.0	1.0 ± 1.0
Basophils	0	0	0	1.0 ± 1.0	1.0 ± 1.0	1.0 ± 1.0
Immature myeloid cells	0	0	0	2.0 ± 1.0^†	0	6.0 ± 3.0^†
No. mice	11	25	12	12	3	8

	Age, mo
	4-8		8-12		15-20
	Wild type	GATA-1^low	Wild type	GATA-1^low	Wild type	GATA-1^low
Hct, %	50.1 ± 3.9	47.2 ± 2.3	48.5 ± 3.4	45.9 ± 4.0	45.3 ± 3.1	39.0 ± 3.9^*
Platelet count, × 10⁹/L	728.0 ± 135.0	118.0 ± 45.0^†	1300.0 ± 270.0	113.0 ± 35.0^†	1,060 ± 189.0	103.0 ± 45.0^†
White cell count, × 10⁹/L	8.1 ± 4.3	4.5 ± 2.8	5.0 ± 1.6	8.0 ± 2.5	6.7 ± 2.3	7.2 ± 1.1
Differential counts, %
Neutrophils	18.0 ± 5.0	25.0 ± 5.0	32.0 ± 12.0	54.0 ± 18.0	39.0 ± 9.0	64.0 ± 5.0^*
Lymphocytes	74.0 ± 12.0	63.0 ± 13.0	60.0 ± 9.0	36.0 ± 11.0	52.0 ± 7.0	22.0 ± 5.0^†
Monocytes	5.0 ± 3.0	10.0 ± 5.0	4.0 ± 2.0	6.0 ± 3.0	5.0 ± 2.0	6.0 ± 1.0
Eosinophils	3.0 ± 2.0	2.0 ± 1.0	2.0 ± 2.0	3.0 ± 2.0	3.0 ± 2.0	1.0 ± 1.0
Basophils	0	0	0	1.0 ± 1.0	1.0 ± 1.0	1.0 ± 1.0
Immature myeloid cells	0	0	0	2.0 ± 1.0^†	0	6.0 ± 3.0^†
No. mice	11	25	12	12	3	8

Immature myeloid cells were represented by metamyelocytes, myelocytes, and occasional promyelocytes.

P < .05;

P < .001.