Estimation of NHL and HD incidence rates and SMRs with French population as a comparison, adjusted for age and sex
| . | Lowest estimation of number of RA patients treated by MTX3-150 (N = 27 000) . | Highest estimation of number of RA patients treated by MTX3-151 (N = 30 000) . | ||
|---|---|---|---|---|
| . | 95% CI . | . | 95% CI . | |
| NHL | ||||
| Incidence rate (per 100 000 person-years) | ||||
| Among men | 37.0 | (0 -89.4) | 33.3 | (0 -80.5) |
| Among women | 18.5 | (0 -37.0) | 16.7 | (0 -33.3) |
| Total | 22.2 | (4.1-40.4) | 20.0 | (3.7-36.3) |
| Comparison with the French national incidence | ||||
| Observed (expected) | 18 (15.1) | 18 (16.7) | ||
| SMR, standardized for age and sex | 1.2 | (0.7 -1.9) | 1.07 | (0.6 -1.7) |
| HD | ||||
| Incidence rate per 100 000 person-years) | ||||
| Among men | 30.9 | (0 -78.7) | 27.8 | (0 -70.8) |
| Among women | 3.1 | (0 -10.6) | 2.8 | (0 -9.6) |
| Total | 8.6 | (0 -20.0) | 7.8 | (0 -18.0) |
| Comparison with the French national incidence | ||||
| Observed (expected) | 7 (0.8) | 7 (0.9) | ||
| SMR, standardized for age and sex (95% CI) | 3-1508.2 | (3.3-17.0) | 3-1507.4 | (3.0-15.3) |
| . | Lowest estimation of number of RA patients treated by MTX3-150 (N = 27 000) . | Highest estimation of number of RA patients treated by MTX3-151 (N = 30 000) . | ||
|---|---|---|---|---|
| . | 95% CI . | . | 95% CI . | |
| NHL | ||||
| Incidence rate (per 100 000 person-years) | ||||
| Among men | 37.0 | (0 -89.4) | 33.3 | (0 -80.5) |
| Among women | 18.5 | (0 -37.0) | 16.7 | (0 -33.3) |
| Total | 22.2 | (4.1-40.4) | 20.0 | (3.7-36.3) |
| Comparison with the French national incidence | ||||
| Observed (expected) | 18 (15.1) | 18 (16.7) | ||
| SMR, standardized for age and sex | 1.2 | (0.7 -1.9) | 1.07 | (0.6 -1.7) |
| HD | ||||
| Incidence rate per 100 000 person-years) | ||||
| Among men | 30.9 | (0 -78.7) | 27.8 | (0 -70.8) |
| Among women | 3.1 | (0 -10.6) | 2.8 | (0 -9.6) |
| Total | 8.6 | (0 -20.0) | 7.8 | (0 -18.0) |
| Comparison with the French national incidence | ||||
| Observed (expected) | 7 (0.8) | 7 (0.9) | ||
| SMR, standardized for age and sex (95% CI) | 3-1508.2 | (3.3-17.0) | 3-1507.4 | (3.0-15.3) |