Toxicities (grade 2 or higher)
| Toxicity . | 200 mg/m2 (n = 23) Frequency, % (n) . | 100 mg/m2 (n = 27) Frequency, % (n) . |
|---|---|---|
| Nausea/vomiting | 83 (19) | 52 (14) |
| Diarrhea | 65 (15) | 48 (13) |
| Mucositis | 91 (21) | 37 (10) |
| Pulmonary edema | 35 (8) | 26 (7) |
| Peripheral edema | 48 (11) | 15 (4) |
| Non-GI bleeding | 71 (4) | 0 (0) |
| GI bleeding | 22 (5) | 7 (2) |
| Hepatic | 13 (3) | 22 (6) |
| Renal | 35 (8) | 19 (5) |
| Metabolic | 35 (8) | 7 (2) |
| Sepsis | 26 (6) | 11 (3) |
| Toxicity . | 200 mg/m2 (n = 23) Frequency, % (n) . | 100 mg/m2 (n = 27) Frequency, % (n) . |
|---|---|---|
| Nausea/vomiting | 83 (19) | 52 (14) |
| Diarrhea | 65 (15) | 48 (13) |
| Mucositis | 91 (21) | 37 (10) |
| Pulmonary edema | 35 (8) | 26 (7) |
| Peripheral edema | 48 (11) | 15 (4) |
| Non-GI bleeding | 71 (4) | 0 (0) |
| GI bleeding | 22 (5) | 7 (2) |
| Hepatic | 13 (3) | 22 (6) |
| Renal | 35 (8) | 19 (5) |
| Metabolic | 35 (8) | 7 (2) |
| Sepsis | 26 (6) | 11 (3) |