Table 1. Summary of the mutations of... | American Society of Hematology

Table 1.

Summary of the mutations of GPIbα

Mutant cell line	Codon changes
D249N/D252N (Comb-3)	GAC to AAC
	GAC to AAC
K253A/K258A/K262A (Comb-2)	AAG to GCG
	AAA to GCA
	AAG to GCG
DEL^*	Deletion of nc 874-894^†
D269N	GAT to AAC
E270Q	GAA to CAA
D272N	GAC to AAC
D274N	GAC to AAC
D277N	GAT to AAT
D277A	GAT to GCT
E281Q	GAA to CAA
E282Q	GAG to CAG
D283N	GAC to AAC
E285Q	GAG to CAA
D287N	GAT to AAT
D283N/E285Q/D287N (Comb-1)	GAC to AAC
	GAG to CAA
	GAT to AAT

Mutant cell line	Codon changes
D249N/D252N (Comb-3)	GAC to AAC
	GAC to AAC
K253A/K258A/K262A (Comb-2)	AAG to GCG
	AAA to GCA
	AAG to GCG
DEL^*	Deletion of nc 874-894^†
D269N	GAT to AAC
E270Q	GAA to CAA
D272N	GAC to AAC
D274N	GAC to AAC
D277N	GAT to AAT
D277A	GAT to GCT
E281Q	GAA to CAA
E282Q	GAG to CAG
D283N	GAC to AAC
E285Q	GAG to CAA
D287N	GAT to AAT
D283N/E285Q/D287N (Comb-1)	GAC to AAC
	GAG to CAA
	GAT to AAT

Single-letter amino acid codes used in the table.

This mutant contains a deletion of the 7 amino acid region from Tyr276 to Glu282.

The nucleotide (nc) count starts from the ATG site.