Table 2.

Adjusted odds ratios for 2C9*3 and 2C9*2 variants and patient age

VariableAdjusted OR95% CIP*
CYP2C9*6.02 1.50 -24.18 .0114  
CYP2C9*2.70 1.11 -6.58 .0284 
Year of age 1.12 1.07 -1.17 < .0001 
VariableAdjusted OR95% CIP*
CYP2C9*6.02 1.50 -24.18 .0114  
CYP2C9*2.70 1.11 -6.58 .0284 
Year of age 1.12 1.07 -1.17 < .0001 

Adjusted ORs are measurements of being at risk of needing a lower dose of acenocoumarol when carrying an allelic variant or when being 1 year older. Patient sex and use of other drugs were finally excluded from the multivariate model because they did not show significant effects (P = .41 and P = .56, respectively) or play a role in any interactions.

CI indicates confidence interval.

*

On Wald testing.

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