Frequencies of cytochrome P-450 2C9 allelic variants in patients with different acenocoumarol-dose requirements
| Variant . | Low dose (n = 43) . | Medium dose (n = 45) . | High dose (n = 21) . |
|---|---|---|---|
| CYP2C9*1/*1 | 30 (71.4) | 43 (95.6) | 20 (95.2) |
| CYP2C9*1/*3 | 11 (26.2) | 2 (4.4) | 1 (4.8) |
| CYP2C9*3/*3 | 1 (2.4) | — | — |
| CYP2C9*1/*1 | 30 (69.8) | 29 (65.9) | 20 (95.2) |
| CYP2C9*1/*2 | 11 (25.6) | 14 (31.8) | 1 (4.8) |
| CYP2C9*2/*2 | 2 (4.6) | 1 (2.3) | — |
| Variant . | Low dose (n = 43) . | Medium dose (n = 45) . | High dose (n = 21) . |
|---|---|---|---|
| CYP2C9*1/*1 | 30 (71.4) | 43 (95.6) | 20 (95.2) |
| CYP2C9*1/*3 | 11 (26.2) | 2 (4.4) | 1 (4.8) |
| CYP2C9*3/*3 | 1 (2.4) | — | — |
| CYP2C9*1/*1 | 30 (69.8) | 29 (65.9) | 20 (95.2) |
| CYP2C9*1/*2 | 11 (25.6) | 14 (31.8) | 1 (4.8) |
| CYP2C9*2/*2 | 2 (4.6) | 1 (2.3) | — |
Values are numbers (%) of patients.