The DNA enzyme had no effect on colony formation of normal bone marrow cells
| Compound . | Colony type . | |||
|---|---|---|---|---|
| G . | GM . | M . | Total . | |
| Nil | 10 ± 3 | 34 ± 7 | 40 ± 8 | 88 ± 6 |
| DOTAP | 11 ± 4 | 41 ± 8 | 37 ± 9 | 90 ± 7 |
| Active DNA enzyme | 13 ± 4 | 41 ± 8 | 39 ± 8 | 91 ± 8 |
| Inactive DNA enzyme | 8 ± 2 | 38 ± 9 | 37 ± 7 | 88 ± 6 |
| Compound . | Colony type . | |||
|---|---|---|---|---|
| G . | GM . | M . | Total . | |
| Nil | 10 ± 3 | 34 ± 7 | 40 ± 8 | 88 ± 6 |
| DOTAP | 11 ± 4 | 41 ± 8 | 37 ± 9 | 90 ± 7 |
| Active DNA enzyme | 13 ± 4 | 41 ± 8 | 39 ± 8 | 91 ± 8 |
| Inactive DNA enzyme | 8 ± 2 | 38 ± 9 | 37 ± 7 | 88 ± 6 |
Values are colony numbers and given as the means ± SEM (n = 6). We cultured 100 000 bone marrow cells supplemented with G-CSF (10 ng/mL) and stem cell factor (10 ng/mL).
G indicates granulocyte; GM, granulocyte/macrophage; M, macrophage.