Genes down-regulated during ATRA/IL-3–induced EML cell differentiation
| Symbol . | Name . | Gene Ontology . |
|---|---|---|
| Gzma | Granzyme A | Apoptosis |
| Pde1b | Phosphodiesterase 1B, Ca2+-calmodulin dependent, 63 kd | Calmodulin binding |
| Vcam1 | Vascular cell adhesion molecule 1 | Cell adhesion |
| Ppm1g | Fibroblast growth factor inducible 13 (FIN13) | Cell cycle |
| Ccng | Cyclin G | Cell cycle control |
| Yes | Yamaguchi sarcoma viral (v-yes) oncogene homolog | Cell cycle regulator |
| Vav2 | Vav2 oncogene | Cell cycle regulator |
| Fos | FBJ osteosarcoma oncogene | Cell cycle regulator |
| Hsp70-2 | Heat shock protein, 70 kd 2 | Chaperone |
| Fosl2 | fos-like antigen 2 | DNA binding |
| Hox11l1 | Homeobox 11-like 1 | DNA binding |
| Rbpsuh | Recombining binding protein suppressor of hairless (Drosophila) | DNA recombination |
| Madh4 | MAD homolog 4 | Morphogenesis |
| Gna13 | Guanine nucleotide binding protein, α 13 | GTP binding |
| Gnao | Guanine nucleotide binding protein, α o | GTP binding |
| Sh3bp1 | SH3 domain-binding protein 1 | GTPase activator |
| Notch1 | Notch gene homolog 1 | Organogenesis |
| Eif2ak2 | Eukaryotic translation initiation factor 2 α kinase 2 | Immune response |
| Scya2 | Small inducible cytokine A2 | Inflammatory response |
| Pla2g7 | Phospholipase A2 group VII (platelet-activating factor acetylhydrolase) | Inflammatory response |
| Apba2 | Amyloid β (A4) precursor protein-binding, family A, member 2 | Intracellular protein traffic |
| Hegfl | Heparin-binding epidermal growth factor-like growth factor | Membrane fraction |
| Kif1b | Kinesin heavy chain member 1B | Microtubule motor |
| Cited2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich C-terminal domain, 2 | Nucleus |
| Psmc4 | Proteasome (prosome, macropain) 26S subunit, ATPase, 4 | Nucleus |
| Crat | Carnitine acetyltransferase | Peroxisome |
| Acox | Acyl-Coenzyme A oxidase | Peroxisome |
| Cd63 | Cd63 antigen | Plasma membrane |
| Cd152 | CD152 antigen | Plasma membrane |
| Cd14 | Cd14 | Posttranslational targeting |
| Ptpn8 | Protein tyrosine phosphatase, nonreceptor type 8 | Protein tyrosine phosphatase |
| Expi | Extracellular proteinase inhibitor | Proteinase inhibitor |
| Es1 | Esterase 1 | Serine esterase |
| Serpinb2 | Serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 2 | Serine protease inhibitor |
| Foxd3 | Forkheadbox D3 | Transcription regulation |
| Hnf4 | Hepatic nuclear factor 4 | Transcription regulation |
| Hoxb4 | Homeobox B4 | Transcription regulation |
| Klf1 | Kruppel-like factor 1 (erythroid) | Transcription regulation |
| Mid1 | Midline 1 | Transcription regulation |
| Nfatc3 | Nuclear factor of activated T cells, cytoplasmic 3 | Transcription regulation |
| Stat4 | Signal transducer and activator of transcription 4 | Transcription regulation |
| Tcf1 | Transcription factor 1 | Transcription regulation |
| Xbp1 | X box binding protein | Transcription regulation |
| Ybx1 | Y box protein 1 | Transcription regulation |
| Zfp038 | Zinc finger protein 38 | Transcription regulation |
| Zfp100 | Zinc finger protein 100 | Transcription regulation |
| Zfp216 | Zinc finger protein 216 | Transcription regulation |
| ZNF183 | Zinc finger protein 183 (RING finger, C3HC4 type) | Transcription regulation |
| Hoxd12 | Homeobox D12 | Transcription regulation |
| LATS2 | Serine/threonine kinase KPM | Tumor suppressor |
| Symbol . | Name . | Gene Ontology . |
|---|---|---|
| Gzma | Granzyme A | Apoptosis |
| Pde1b | Phosphodiesterase 1B, Ca2+-calmodulin dependent, 63 kd | Calmodulin binding |
| Vcam1 | Vascular cell adhesion molecule 1 | Cell adhesion |
| Ppm1g | Fibroblast growth factor inducible 13 (FIN13) | Cell cycle |
| Ccng | Cyclin G | Cell cycle control |
| Yes | Yamaguchi sarcoma viral (v-yes) oncogene homolog | Cell cycle regulator |
| Vav2 | Vav2 oncogene | Cell cycle regulator |
| Fos | FBJ osteosarcoma oncogene | Cell cycle regulator |
| Hsp70-2 | Heat shock protein, 70 kd 2 | Chaperone |
| Fosl2 | fos-like antigen 2 | DNA binding |
| Hox11l1 | Homeobox 11-like 1 | DNA binding |
| Rbpsuh | Recombining binding protein suppressor of hairless (Drosophila) | DNA recombination |
| Madh4 | MAD homolog 4 | Morphogenesis |
| Gna13 | Guanine nucleotide binding protein, α 13 | GTP binding |
| Gnao | Guanine nucleotide binding protein, α o | GTP binding |
| Sh3bp1 | SH3 domain-binding protein 1 | GTPase activator |
| Notch1 | Notch gene homolog 1 | Organogenesis |
| Eif2ak2 | Eukaryotic translation initiation factor 2 α kinase 2 | Immune response |
| Scya2 | Small inducible cytokine A2 | Inflammatory response |
| Pla2g7 | Phospholipase A2 group VII (platelet-activating factor acetylhydrolase) | Inflammatory response |
| Apba2 | Amyloid β (A4) precursor protein-binding, family A, member 2 | Intracellular protein traffic |
| Hegfl | Heparin-binding epidermal growth factor-like growth factor | Membrane fraction |
| Kif1b | Kinesin heavy chain member 1B | Microtubule motor |
| Cited2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich C-terminal domain, 2 | Nucleus |
| Psmc4 | Proteasome (prosome, macropain) 26S subunit, ATPase, 4 | Nucleus |
| Crat | Carnitine acetyltransferase | Peroxisome |
| Acox | Acyl-Coenzyme A oxidase | Peroxisome |
| Cd63 | Cd63 antigen | Plasma membrane |
| Cd152 | CD152 antigen | Plasma membrane |
| Cd14 | Cd14 | Posttranslational targeting |
| Ptpn8 | Protein tyrosine phosphatase, nonreceptor type 8 | Protein tyrosine phosphatase |
| Expi | Extracellular proteinase inhibitor | Proteinase inhibitor |
| Es1 | Esterase 1 | Serine esterase |
| Serpinb2 | Serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 2 | Serine protease inhibitor |
| Foxd3 | Forkheadbox D3 | Transcription regulation |
| Hnf4 | Hepatic nuclear factor 4 | Transcription regulation |
| Hoxb4 | Homeobox B4 | Transcription regulation |
| Klf1 | Kruppel-like factor 1 (erythroid) | Transcription regulation |
| Mid1 | Midline 1 | Transcription regulation |
| Nfatc3 | Nuclear factor of activated T cells, cytoplasmic 3 | Transcription regulation |
| Stat4 | Signal transducer and activator of transcription 4 | Transcription regulation |
| Tcf1 | Transcription factor 1 | Transcription regulation |
| Xbp1 | X box binding protein | Transcription regulation |
| Ybx1 | Y box protein 1 | Transcription regulation |
| Zfp038 | Zinc finger protein 38 | Transcription regulation |
| Zfp100 | Zinc finger protein 100 | Transcription regulation |
| Zfp216 | Zinc finger protein 216 | Transcription regulation |
| ZNF183 | Zinc finger protein 183 (RING finger, C3HC4 type) | Transcription regulation |
| Hoxd12 | Homeobox D12 | Transcription regulation |
| LATS2 | Serine/threonine kinase KPM | Tumor suppressor |
Some abbreviations are explained in the Table 3footnote.