Effect of third-party bone marrow stromal cells containing variable percentages of CD14+ cells on T-cell proliferation
| MLRs* . | Stimulation index (mean ± SD) . |
|---|---|
| T cells + PBLs | 36 ± 2 |
| T cells + PBLs + BMSCs containing 34% CD14+ cells | 51 ± 4† |
| T cells + PBLs + BMSCs containing 4% CD14+cells | 10 ± 1‡ |
| MLRs* . | Stimulation index (mean ± SD) . |
|---|---|
| T cells + PBLs | 36 ± 2 |
| T cells + PBLs + BMSCs containing 34% CD14+ cells | 51 ± 4† |
| T cells + PBLs + BMSCs containing 4% CD14+cells | 10 ± 1‡ |
MLR, mixed lymphocyte reaction; PBL, peripheral blood lymphocyte; BMSC, bone marrow stromal cell.
CD2+ (5 × 104) T cells were mixed at 1:1 ratio with allogeneic PBLs ± BMSCs.
Significantly increased as compared with MLRs without BMSCs (P = .001).
Significantly decreased as compared with MLRs without BMSCs (P = .001).