Table 2. Summary of the AML patients... | American Society of Hematology

Table 2.

Summary of the AML patients screened for PU.1 mutations

AML phenotype	FAB	n^2-155	Mutations
Undifferentiated	M0	13	3
Myeloblastic	M1	8	1^2-153
	M2	23^*	0
Promyelocytic	M3	11^‡	0
Myelomonocytic	M4	49^†	3
Monoblastic	M5	14	1
Erythroleukemia	M6	6	1
AUL		2	0
Total		126

AML phenotype	FAB	n^2-155	Mutations
Undifferentiated	M0	13	3
Myeloblastic	M1	8	1^2-153
	M2	23^*	0
Promyelocytic	M3	11^‡	0
Myelomonocytic	M4	49^†	3
Monoblastic	M5	14	1
Erythroleukemia	M6	6	1
AUL		2	0
Total		126

Subtypes according to the French-American-British (FAB) classification.

Of the 23 M2 patients, 3 were positive for the AML1-ETO translocation.

Of the 49 M4 patients, 10 carried the inv(16).

All 11 M3 patients had the PML-RARA translocation.

This patient was originally classified as M4.

n indicates the number of patients with this subtype.