Proportion of Gr-1+ cells and neutrophils in the bone marrow as determined by FACScan and morphological analysis, respectively
| Genotype of mice . | Bone marrow cellularity, × 107 . | Percentage of total Gr-1+ cells . | Percentage of Gr-1lo* cells . | Percentage of Gr-1high* cells . | Percentage of neutrophils, total . | Percentage of promyelocytes + myelocytes . | Percentage of metamyelocyte + bands + polymorphs . |
|---|---|---|---|---|---|---|---|
| Wild type | 1.85 ± 0.3 | 52 ± 3.4 | 15 ± 2.3 | 36 ± 0.5 | 45 ± 3.0 | 15 ± 2.5 | 30 ± 2 |
| G-CSF−/− | 1.5 ± 0.5 | 32 ± 3.6 | 14 ± 1.4 | 17 ± 1.2 | 29 ± 4.6 | 15 ± 3.8 | 14 ± 2 |
| Genotype of mice . | Bone marrow cellularity, × 107 . | Percentage of total Gr-1+ cells . | Percentage of Gr-1lo* cells . | Percentage of Gr-1high* cells . | Percentage of neutrophils, total . | Percentage of promyelocytes + myelocytes . | Percentage of metamyelocyte + bands + polymorphs . |
|---|---|---|---|---|---|---|---|
| Wild type | 1.85 ± 0.3 | 52 ± 3.4 | 15 ± 2.3 | 36 ± 0.5 | 45 ± 3.0 | 15 ± 2.5 | 30 ± 2 |
| G-CSF−/− | 1.5 ± 0.5 | 32 ± 3.6 | 14 ± 1.4 | 17 ± 1.2 | 29 ± 4.6 | 15 ± 3.8 | 14 ± 2 |
Gr-1lo and Gr-1high represent cells expressing low and high levels of Gr-1, respectively.
Values are represented as mean ± SD; n = 6 for each group.