Log-rank test of clinical and genetic data with patient outcome
| Variable . | Status (no. patients) . | EFS rate at 24 mo [CI] . | P . |
|---|---|---|---|
| HOX11L2 | + (6) | 20 [0.8-58] | .02 |
| − (22) | 89 [64-97] | ||
| SIL-TAL1 | + (6) | 62 [29-83] | .75 |
| − (22) | 80 [20-97] | ||
| p16 | Homozygous deletion (14) | 56 [19-82] | .18 |
| Other (11) | 80 [20-97] | ||
| LYL1 | + (14) | 74 [38-91] | .74 |
| − (10) | 60 [8-90] | ||
| LMO2 | + (9) | 89 [43-98] | .14 |
| − (15) | 42 [6-76] | ||
| TAL1 | + (13) | 80 [40-95] | .25 |
| − (12) | 53 [8-85] | ||
| WBC (109/L) | < 50 (10) | 100 | .05 |
| > 50 (18) | 50 [20-74] | ||
| Age (year) | < 9 (18) | 65 [30-86] | .92 |
| > 9 (10) | 71 [23-92] | ||
| Sex | F (12) | 70 [32-89] | .98 |
| M (16) | 62 [20-87] | ||
| CH R | − (23) | 80 [20-97] | .75 |
| + (5) | 63 [39-83] | ||
| CO R | − (16) | 86 [33-98] | .15 |
| + (11) | 53 [19-79] | ||
| CD1a | − (6) | 80 [20-97] | .85 |
| + (13) | 60 [19-85] | ||
| CD4 | − (11) | 90 [47-98] | .43 |
| + (17) | 60 [29-81] | ||
| CD8 | − (10) | 67 [5-94] | .31 |
| + (18) | 62 [30-82] | ||
| CD3 | − (12) | 89 [5-94] | .16 |
| + (14) | 56 [19-82] | ||
| CD34 | − (16) | 74 [38-91] | .57 |
| + (12) | 54 [13-83] |
| Variable . | Status (no. patients) . | EFS rate at 24 mo [CI] . | P . |
|---|---|---|---|
| HOX11L2 | + (6) | 20 [0.8-58] | .02 |
| − (22) | 89 [64-97] | ||
| SIL-TAL1 | + (6) | 62 [29-83] | .75 |
| − (22) | 80 [20-97] | ||
| p16 | Homozygous deletion (14) | 56 [19-82] | .18 |
| Other (11) | 80 [20-97] | ||
| LYL1 | + (14) | 74 [38-91] | .74 |
| − (10) | 60 [8-90] | ||
| LMO2 | + (9) | 89 [43-98] | .14 |
| − (15) | 42 [6-76] | ||
| TAL1 | + (13) | 80 [40-95] | .25 |
| − (12) | 53 [8-85] | ||
| WBC (109/L) | < 50 (10) | 100 | .05 |
| > 50 (18) | 50 [20-74] | ||
| Age (year) | < 9 (18) | 65 [30-86] | .92 |
| > 9 (10) | 71 [23-92] | ||
| Sex | F (12) | 70 [32-89] | .98 |
| M (16) | 62 [20-87] | ||
| CH R | − (23) | 80 [20-97] | .75 |
| + (5) | 63 [39-83] | ||
| CO R | − (16) | 86 [33-98] | .15 |
| + (11) | 53 [19-79] | ||
| CD1a | − (6) | 80 [20-97] | .85 |
| + (13) | 60 [19-85] | ||
| CD4 | − (11) | 90 [47-98] | .43 |
| + (17) | 60 [29-81] | ||
| CD8 | − (10) | 67 [5-94] | .31 |
| + (18) | 62 [30-82] | ||
| CD3 | − (12) | 89 [5-94] | .16 |
| + (14) | 56 [19-82] | ||
| CD34 | − (16) | 74 [38-91] | .57 |
| + (12) | 54 [13-83] |
CI indicates confidence interval; CH R, chemical resistance; CO R, cortisone resistance.