Outcome following unrelated donor BMT for SAA: multivariate analysis
| Covariates . | Relative risk (95% CI) . | P . |
|---|---|---|
| Graft failure | ||
| Recipient 20 y or more | 2.86 (0.94-8.44) | .06 |
| Non-TBI regimen | 3.94 (1.26-12.4) | .01 |
| HLA-A or -B locus mismatching | 2.43 (0.78-7.46) | .12 |
| Grade III/IV acute GVHD | ||
| Male donor | 3.45 (0.95-12.5) | .06 |
| Non-ATG regimen | 4.21 (1.36-13.1) | .01 |
| HLA-A or -B locus mismatching | 3.32 (1.09-10.1) | .03 |
| Chronic GVHD | ||
| HLA-A or -B locus mismatching | 6.62 (1.76-25.0) | .005 |
| Grade II-IV acute GVHD | 6.29 (1.55-25.5) | .01 |
| 5-year survival | ||
| Recipient 20 y or more | 2.27 (1.08-4.81) | .03 |
| Male donor | 2.81 (0.94-5.63) | .07 |
| Disease duration 3 y or more | 1.86 (1.11-3.14) | .02 |
| Non-ATG regimen | 2.28 (1.06-4.91) | .03 |
| HLA-A or -B locus mismatching | 2.28 (1.04-5.02) | .04 |
| Covariates . | Relative risk (95% CI) . | P . |
|---|---|---|
| Graft failure | ||
| Recipient 20 y or more | 2.86 (0.94-8.44) | .06 |
| Non-TBI regimen | 3.94 (1.26-12.4) | .01 |
| HLA-A or -B locus mismatching | 2.43 (0.78-7.46) | .12 |
| Grade III/IV acute GVHD | ||
| Male donor | 3.45 (0.95-12.5) | .06 |
| Non-ATG regimen | 4.21 (1.36-13.1) | .01 |
| HLA-A or -B locus mismatching | 3.32 (1.09-10.1) | .03 |
| Chronic GVHD | ||
| HLA-A or -B locus mismatching | 6.62 (1.76-25.0) | .005 |
| Grade II-IV acute GVHD | 6.29 (1.55-25.5) | .01 |
| 5-year survival | ||
| Recipient 20 y or more | 2.27 (1.08-4.81) | .03 |
| Male donor | 2.81 (0.94-5.63) | .07 |
| Disease duration 3 y or more | 1.86 (1.11-3.14) | .02 |
| Non-ATG regimen | 2.28 (1.06-4.91) | .03 |
| HLA-A or -B locus mismatching | 2.28 (1.04-5.02) | .04 |