Values are numbers of patients.

KSHV positivity was determined by latency-associated nuclear antigen-specific serologic assessment as described previously.2 

The MM ORF65 antigen pool included the 4 peptides spanning the described MM-KSHV ORF65 sequence C-terminal to the stop codon in the previously reported ORF65.

Only those with a response to EBV are included in the table. However, 11 patients with MM who had no response to EBV were also negative for ORF65-specific and ORF73-specific responses on ELISPOT assays.

ELISPOT responses were considered positive if values were higher than 15 spot-forming cells (SFCs)/10⁶ PBMCs. The range for positive ORF73-specific responses was 257 to 1280 SFCs/10⁶ PBMCs, that for ORF65-specific responses was 40 to 120 SFCs/10⁶ PBMCs, and that for positive EBV responses was 25 to 1500 SFCs/10⁶ PBMCs.