Clinical characteristics of chronic hepatitis B patients treated with prophylactic lamivudine
| Patient no. . | Sex . | Age, y . | Basic disease . | Immunosuppressive treatment . | Outcome . |
|---|---|---|---|---|---|
| 1 | F | 49 | Lymphoma | CHOP* | Alive |
| 2 | F | 65 | Lymphoma | CHOP* | Alive |
| 3 | M | 44 | Enophtalmitis | Steroids† | Alive |
| 4 | M | 57 | Lymphoma | Cyclophosphamide, vincristine, prednisone‡ | Died |
| 5 | M | 57 | Cryoglobulinemia | Steroids† | Alive |
| 6 | M | 62 | Colon carcinoma | 5-FU1-153 | Alive |
| 7 | M | 38 | Lymphoma | CHOP* | Died |
| 8 | M | 55 | Lymphoma | CHOP* | Alive |
| 9 | M | 56 | Colon carcinoma | 5-FU1-153 | Alive |
| 10 | M | 65 | Lymphoma | Chlorambucil1-155 | Alive |
| 11 | M | 52 | Vasculitis | Steroids,†cyclophosphamide1-154 | Alive |
| 12 | M | 42 | Lymphoma | CHOP* | Died |
| 13 | F | 47 | Ulcerative colitis | Steroids† | Alive |
| Patient no. . | Sex . | Age, y . | Basic disease . | Immunosuppressive treatment . | Outcome . |
|---|---|---|---|---|---|
| 1 | F | 49 | Lymphoma | CHOP* | Alive |
| 2 | F | 65 | Lymphoma | CHOP* | Alive |
| 3 | M | 44 | Enophtalmitis | Steroids† | Alive |
| 4 | M | 57 | Lymphoma | Cyclophosphamide, vincristine, prednisone‡ | Died |
| 5 | M | 57 | Cryoglobulinemia | Steroids† | Alive |
| 6 | M | 62 | Colon carcinoma | 5-FU1-153 | Alive |
| 7 | M | 38 | Lymphoma | CHOP* | Died |
| 8 | M | 55 | Lymphoma | CHOP* | Alive |
| 9 | M | 56 | Colon carcinoma | 5-FU1-153 | Alive |
| 10 | M | 65 | Lymphoma | Chlorambucil1-155 | Alive |
| 11 | M | 52 | Vasculitis | Steroids,†cyclophosphamide1-154 | Alive |
| 12 | M | 42 | Lymphoma | CHOP* | Died |
| 13 | F | 47 | Ulcerative colitis | Steroids† | Alive |
The CHOP regimen was as follows: cyclophosphamide (750 mg/m2); vincristine (Oncovin) (1.4 mg/m2); doxorubicin (Adriamycin) (50 mg/m2) on day 1; and prednisone (100 mg) on days 1-5.
1 mg/kg prednisone by mouth (PO) and then tapering down.
Modified CHOP (the doses of the other medications remain the same as in the regular CHOP).
900 mg/m2 5-fluorouracil intravenously every 2 weeks.
8 mg/day PO for 4 days every month.
1 mg/kg every day PO.