Frequency of lymphocytes in PECAM-1+/+ vs PECAM-1−/− mice
| Tissue type . | Phenotype . | % of lymphoid cells,* PECAM-1+/+ . | % of lymphoid cells,* PECAM-1−/− . | P . | No. of mice analyzed . |
|---|---|---|---|---|---|
| Bone marrow | CD43+B220+ | 5.6 ± 1.2 | 7.9 ± 2.3 | > .05 | 12 |
| IgM+IgDlow | 17.2 ± 5.4 | 21.8 ± 7.2 | > .05 | 12 | |
| IgM+IgDhigh | 21.6 ± 7.4 | 11.8 ± 4.8 | < .001 | 12 | |
| Spleen | B220+ | 63.8 ± 6.2 | 55.9 ± 3.3 | < .001 | 44 |
| IgM+ | 62.9 ± 6.2 | 58.4 ± 8.5 | > .05 | 25 | |
| IgD+ | 52.1 ± 6.7 | 44.7 ± 4.1 | < .005 | 25 | |
| B220+IgM+ | 52.8 ± 7.2 | 51.6 ± 5.6 | > .05 | 12 | |
| B220+IgDlow | 14.6 ± 4.7 | 15.4 ± 6.8 | > .05 | 12 | |
| B220+IgDhigh | 34.2 ± 5.6 | 19.4 ± 7.2 | < .001 | 12 | |
| CD3+ | 26.0 ± 3.8 | 29.2 ± 11.1 | > .05 | 25 | |
| Peritoneum | B220lowCD5+ | 20.7 ± 5.6 | 31.6 ± 6.4 | < .001 | 25 |
| Tissue type . | Phenotype . | % of lymphoid cells,* PECAM-1+/+ . | % of lymphoid cells,* PECAM-1−/− . | P . | No. of mice analyzed . |
|---|---|---|---|---|---|
| Bone marrow | CD43+B220+ | 5.6 ± 1.2 | 7.9 ± 2.3 | > .05 | 12 |
| IgM+IgDlow | 17.2 ± 5.4 | 21.8 ± 7.2 | > .05 | 12 | |
| IgM+IgDhigh | 21.6 ± 7.4 | 11.8 ± 4.8 | < .001 | 12 | |
| Spleen | B220+ | 63.8 ± 6.2 | 55.9 ± 3.3 | < .001 | 44 |
| IgM+ | 62.9 ± 6.2 | 58.4 ± 8.5 | > .05 | 25 | |
| IgD+ | 52.1 ± 6.7 | 44.7 ± 4.1 | < .005 | 25 | |
| B220+IgM+ | 52.8 ± 7.2 | 51.6 ± 5.6 | > .05 | 12 | |
| B220+IgDlow | 14.6 ± 4.7 | 15.4 ± 6.8 | > .05 | 12 | |
| B220+IgDhigh | 34.2 ± 5.6 | 19.4 ± 7.2 | < .001 | 12 | |
| CD3+ | 26.0 ± 3.8 | 29.2 ± 11.1 | > .05 | 25 | |
| Peritoneum | B220lowCD5+ | 20.7 ± 5.6 | 31.6 ± 6.4 | < .001 | 25 |
Mean percentage ± SD of the mean for each phenotype examined.