Treatment burden according to treatment phase
| . | Protocol Ia . | Protocol Ib . | Consolidation blocks . | Protocol II, 1st . | Protocol II, 2nd . |
|---|---|---|---|---|---|
| No. patients analyzed | 182 | 157 | 124 | 109 | 31 |
| Red blood cells | |||||
| Patients receiving at least 1 U, % | 85 | 96 | 90 | 69 | 65 |
| No. units, mean | 2.9 | 3.1 | 3.7 | 2.4 | 2.1 |
| Platelets | |||||
| Patients receiving at least 1 U, % | 51 | 36 | 70 | 16 | 23 |
| No. units, mean | 4.3 | 3.6 | 5.1 | 3.6 | 3.4 |
| IV antibiotic therapy | |||||
| Patients, % | 46 | 37 | 82 | 46 | 74 |
| Duration in days, mean | 11 | 7 | 14 | 9 | 14 |
| Central venous line | |||||
| Patients, % | 67 | 75 | 83 | 80 | 74 |
| No. days, mean | 35 | 50 | 68 | 74 | 78 |
| Hospitalization | |||||
| Patients, % | 97 | 85 | 99 | 85 | 87 |
| No. days, mean | 22 | 14 | 32 | 11 | 19 |
| Phase duration, days | |||||
| Scheduled by protocol | 42 | 42 | 63 | 64 | 64 |
| Observed, mean | 46 | 59 | 73 | 81 | 89 |
| . | Protocol Ia . | Protocol Ib . | Consolidation blocks . | Protocol II, 1st . | Protocol II, 2nd . |
|---|---|---|---|---|---|
| No. patients analyzed | 182 | 157 | 124 | 109 | 31 |
| Red blood cells | |||||
| Patients receiving at least 1 U, % | 85 | 96 | 90 | 69 | 65 |
| No. units, mean | 2.9 | 3.1 | 3.7 | 2.4 | 2.1 |
| Platelets | |||||
| Patients receiving at least 1 U, % | 51 | 36 | 70 | 16 | 23 |
| No. units, mean | 4.3 | 3.6 | 5.1 | 3.6 | 3.4 |
| IV antibiotic therapy | |||||
| Patients, % | 46 | 37 | 82 | 46 | 74 |
| Duration in days, mean | 11 | 7 | 14 | 9 | 14 |
| Central venous line | |||||
| Patients, % | 67 | 75 | 83 | 80 | 74 |
| No. days, mean | 35 | 50 | 68 | 74 | 78 |
| Hospitalization | |||||
| Patients, % | 97 | 85 | 99 | 85 | 87 |
| No. days, mean | 22 | 14 | 32 | 11 | 19 |
| Phase duration, days | |||||
| Scheduled by protocol | 42 | 42 | 63 | 64 | 64 |
| Observed, mean | 46 | 59 | 73 | 81 | 89 |
Mean values were estimated including only patients who actually required the specific support.
Consolidation blocks data presented pertain to the entire phase (3 blocks).
Central venous line data are cumulative.