Table 2. Frequencies of HLA-DRB1, -DQA1,... | American Society of Hematology

Table 2.

Frequencies of HLA-DRB1, -DQA1, and -DQB1 alleles in PNH and AA patients and Japanese healthy controls

Gene allele^*		Frequency of each allele, %
Gene allele^*		PNH (n = 21)	AA (n = 21)	Healthy controls (n = 916)
DRB1	0101	2.4	2.4	4.8
	0406	7.1	2.4	3.2
	0901	9.5	16.7	12.4
	1101	2.4	4.8	2.9
	1201	4.8	7.1	3.9
	1302	7.1	7.1	5.3
	1401	7.1	0	4.5
	1501	33.3	16.7	6.1
	1502	14.3	14.3	8.7
	04051	7.1	14.3	15.5
	08032	4.8	4.8	7.6
DQA1	0101	2.4	2.4	12.3^†
	0104	7.1	2.4	12.3^†
	0102	40.5	21.4	12.1
	0103	19.0	21.4	16.9
	03011	7.1	2.4	42.3^†
	0302	9.5	21.4	42.3^†
	0303	7.1	16.7	42.3^†
	0505	7.1	7.1	8.7^†
DQB1	0301	4.8	9.5	13.1
	0302	9.5	2.4	11.8
	0401	7.1	16.7	15.1
	0501	2.4	4.8	5.4
	0601	19.0	19.0	16.1
	0602	33.3	16.7	6.0
	0604	7.1	4.8	5.0
	03032	9.5	21.4	11.2
	05031	7.1	2.4	5.0

Gene allele^*		Frequency of each allele, %
Gene allele^*		PNH (n = 21)	AA (n = 21)	Healthy controls (n = 916)
DRB1	0101	2.4	2.4	4.8
	0406	7.1	2.4	3.2
	0901	9.5	16.7	12.4
	1101	2.4	4.8	2.9
	1201	4.8	7.1	3.9
	1302	7.1	7.1	5.3
	1401	7.1	0	4.5
	1501	33.3	16.7	6.1
	1502	14.3	14.3	8.7
	04051	7.1	14.3	15.5
	08032	4.8	4.8	7.6
DQA1	0101	2.4	2.4	12.3^†
	0104	7.1	2.4	12.3^†
	0102	40.5	21.4	12.1
	0103	19.0	21.4	16.9
	03011	7.1	2.4	42.3^†
	0302	9.5	21.4	42.3^†
	0303	7.1	16.7	42.3^†
	0505	7.1	7.1	8.7^†
DQB1	0301	4.8	9.5	13.1
	0302	9.5	2.4	11.8
	0401	7.1	16.7	15.1
	0501	2.4	4.8	5.4
	0601	19.0	19.0	16.1
	0602	33.3	16.7	6.0
	0604	7.1	4.8	5.0
	03032	9.5	21.4	11.2
	05031	7.1	2.4	5.0

The alleles shown here were found in at least 2 of the 42 patients.

†

DQA1∗0101, DQA1∗0301, and DQA1∗0501 determined by Hashimoto et al57 include DQA1∗0101, 0104, and (0105); DQA1∗03011, 0302, and 0303; and DQA1∗(0501) and 0505, respectively.

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