Table 1. Clinical and laboratory... | American Society of Hematology

Table 1.

Clinical and laboratory characteristics in patients with essential thrombocythemia, according to pattern of c-mplexpression

Characteristic	All patients, n = 88	Pattern of c-mpl expression			P
Characteristic	All patients, n = 88	Uniform; n = 28, 32% of all	Heterogeneous-moderate; n = 30, 34% of all	Heterogeneous-weak; n = 30, 34% of all	P
Sex: M/F (ratio)	39/49 (0.79)	11/17 (0.64)	15/15 (1.00)	13/17 (0.76)	.691
Median age, y (range)	53 (16-84)	53 (22-80)	56 (19-84)	48 (16-77)	.405
Median Hb, g/L (range)	13.9 (102-186)	139 (102-175)	136 (112-186)	140 (108-164)	.928
Median Hct (range)	0.42 (0.3-0.55)	0.42 (0.3-0.52)	0.41 (0.32-0.55)	0.42 (0.37-0.48)	.954
Median PLT count, 10⁹/L (range)	775 (350-1673)^*	747 (505-1415)	780 (601-1673)	793 (350-1600)^*	.212
Median WBC count, 10⁹/L (range)	8.5 (4.8-28.8)	7.7 (4.8-12.0)	8.6 (5.1-16.8)	8.9 (5.5-28.8)	.045
No. BM hypercellularity (%)	56 (64)	13 (46)	23 (77)	20 (67)	.052
No. with splenomegaly (%)^†	25 (28)	5 (18)	13 (43)	7 (23)	.074
No. with thrombosis (%)	20 (23)	2 (7)	5 (17)	13 (43)	.020

Characteristic	All patients, n = 88	Pattern of c-mpl expression			P
Characteristic	All patients, n = 88	Uniform; n = 28, 32% of all	Heterogeneous-moderate; n = 30, 34% of all	Heterogeneous-weak; n = 30, 34% of all	P
Sex: M/F (ratio)	39/49 (0.79)	11/17 (0.64)	15/15 (1.00)	13/17 (0.76)	.691
Median age, y (range)	53 (16-84)	53 (22-80)	56 (19-84)	48 (16-77)	.405
Median Hb, g/L (range)	13.9 (102-186)	139 (102-175)	136 (112-186)	140 (108-164)	.928
Median Hct (range)	0.42 (0.3-0.55)	0.42 (0.3-0.52)	0.41 (0.32-0.55)	0.42 (0.37-0.48)	.954
Median PLT count, 10⁹/L (range)	775 (350-1673)^*	747 (505-1415)	780 (601-1673)	793 (350-1600)^*	.212
Median WBC count, 10⁹/L (range)	8.5 (4.8-28.8)	7.7 (4.8-12.0)	8.6 (5.1-16.8)	8.9 (5.5-28.8)	.045
No. BM hypercellularity (%)	56 (64)	13 (46)	23 (77)	20 (67)	.052
No. with splenomegaly (%)^†	25 (28)	5 (18)	13 (43)	7 (23)	.074
No. with thrombosis (%)	20 (23)	2 (7)	5 (17)	13 (43)	.020

Hb indicates hemoglobin; Hct, hematocrit; PLT, platelet; WBC, white blood cell; and BM, bone marrow.

The low limit of the range represents the results in the patient with latent chronic myeloproliferative disease.

The spleen size was evaluated with use of ultrasonography.