Table 1.

Characteristics of patients, according to transplant arm

CharacteristicBMT
(n = 32)
PBSCT
(n = 39)
Patient age, median y (range) 42  (12-55) 45  (23-55)  
Donor age, median y (range) 45  (15-61) 43  (19-61)  
Donor/recipient sex, no. (%)   
 Male/male 12  (38) 10  (26) 
 Male/female 4  (13) 7  (18)  
 Female/female 6  (19) 8  (21)  
 Female/male 10  (31) 14  (36) 
Disease at transplantation, no. (%)   
 High risk* 14  (44) 17  (44)  
 Low risk 18  (56) 22  (56)  
Transplanted donor cells, median (range)   
 CD34 × 10−6/kg of recipient weight 2.5  (1.0-4.8) 6.9  (1.0-29.8)  
 CD3 × 10−8/kg of recipient weight 0.2  (0.1-0.4) 2.6  (1.7-7.9)  
Grade of acute GVHD, no. (%)   
 0 8  (25) 10  (26)  
 I-II 22  (69) 23  (59) 
 II-IV 2  (6) 6  (15)  
Follow up from transplantation, median mo (range) 41  (26-63) 40  (25-62) 
CharacteristicBMT
(n = 32)
PBSCT
(n = 39)
Patient age, median y (range) 42  (12-55) 45  (23-55)  
Donor age, median y (range) 45  (15-61) 43  (19-61)  
Donor/recipient sex, no. (%)   
 Male/male 12  (38) 10  (26) 
 Male/female 4  (13) 7  (18)  
 Female/female 6  (19) 8  (21)  
 Female/male 10  (31) 14  (36) 
Disease at transplantation, no. (%)   
 High risk* 14  (44) 17  (44)  
 Low risk 18  (56) 22  (56)  
Transplanted donor cells, median (range)   
 CD34 × 10−6/kg of recipient weight 2.5  (1.0-4.8) 6.9  (1.0-29.8)  
 CD3 × 10−8/kg of recipient weight 0.2  (0.1-0.4) 2.6  (1.7-7.9)  
Grade of acute GVHD, no. (%)   
 0 8  (25) 10  (26)  
 I-II 22  (69) 23  (59) 
 II-IV 2  (6) 6  (15)  
Follow up from transplantation, median mo (range) 41  (26-63) 40  (25-62) 
*

Low-risk diseases included acute myeloid or lymphoid leukemia in first remission, CML in chronic phase, lymphoma in first or second remission or untreated first relapse, and refractory anemia.

High-risk diseases included all other diseases and stages.

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