Table 3. Platelet-dense granule adenine... | American Society of Hematology

Table 3.

Platelet-dense granule adenine nucleotides are significantly reduced in C3H/HeSnJ ash/ash mice

	ATP (μmol/10¹¹ platelets)	ADP (μmol/10¹¹ platelets)	ATP/ADP
C3H/HeSnJ +/+	4.37 ± 0.18 (16)	2.40 ± 0.15 (16)	1.82
C3H/HeSnJash/ash	3.03 ± 0.27 (7)^3-150	1.08 ± 0.11 (7)^3-151	2.80
C57BL/6J +/+	5.72 ± 0.71 (8)	3.34 ± 0.29 (8)	1.77
a/a, ash/ash	4.80 ± 0.23 (5)	2.28 ± 0.21 (5)	2.10

	ATP (μmol/10¹¹ platelets)	ADP (μmol/10¹¹ platelets)	ATP/ADP
C3H/HeSnJ +/+	4.37 ± 0.18 (16)	2.40 ± 0.15 (16)	1.82
C3H/HeSnJash/ash	3.03 ± 0.27 (7)^3-150	1.08 ± 0.11 (7)^3-151	2.80
C57BL/6J +/+	5.72 ± 0.71 (8)	3.34 ± 0.29 (8)	1.77
a/a, ash/ash	4.80 ± 0.23 (5)	2.28 ± 0.21 (5)	2.10

Adenosine triphosphate (ATP) and adenosine diphosphate (ADP) were assayed with a modified luciferase assay. Values represent the mean ± SEM of the number of mice in parentheses.

F3-150

P < .01.

F3-151

P < .001 (compared with C3H/HeSnJ +/+ controls).

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