Table 3.

Chimerism and tumor responses of the 11 patients with hematologic malignancies treated with a sibling graft

Patient no.DiseaseDonor chimerismDisease state at 8 wkSurvival days
Wk 1Wk 2Wk 3Wk 4Wk 8
Lymphoma 5% CR 12853-150 
Lymphoma 10% 10% Not obtained Patient died of progressive disease   28 
Myeloma Not obtained 100% 100% CR 116 
Myeloma 10% 10% Stable 229 
CML 67% 5% 5% No response 129 
11 Lymphoma 5% Not obtained Not obtained Patient died of progressive disease   29 
12 Lymphoma 10% 40% 90% 100% 100% CR 222 
20 Lymphoma 67% Patient died of progressive disease  37 
23 CLL PR 179 
24 Lymphoma Patient died of progressive disease  40 
25 AML 100% 100% 100% 100% CR 6303-150 
Patient no.DiseaseDonor chimerismDisease state at 8 wkSurvival days
Wk 1Wk 2Wk 3Wk 4Wk 8
Lymphoma 5% CR 12853-150 
Lymphoma 10% 10% Not obtained Patient died of progressive disease   28 
Myeloma Not obtained 100% 100% CR 116 
Myeloma 10% 10% Stable 229 
CML 67% 5% 5% No response 129 
11 Lymphoma 5% Not obtained Not obtained Patient died of progressive disease   29 
12 Lymphoma 10% 40% 90% 100% 100% CR 222 
20 Lymphoma 67% Patient died of progressive disease  37 
23 CLL PR 179 
24 Lymphoma Patient died of progressive disease  40 
25 AML 100% 100% 100% 100% CR 6303-150 

CML indicates chronic myelogenous leukemia.

F3-150

Patient alive at last follow-up of December 31, 2001.

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