Table 2.

Prior chemotherapy

Unique patient IDDiagnosisNo. of prior regimensChemotherapyRadiation
Solid tumor patients 
Esophageal cancer 1.  5-FU/cisplatin Yes 
Hepatocellular  No 
Neuroendocrine 1.  VP-16/cisplatin No 
   2.  Carbo/Taxol/VP-16  
Adrenocortical 1.  Mitotane Yes 
10 Sarcoma  Yes  
13 Melanoma  Yes 
15 Lung 1.  Cisplatin/etoposide No 
   2.  Topotecan  
   3.  Taxol/Carbo  
16 Pancreatic 1.  Taxol Yes 
17 Renal cell  Yes 
18 Esophageal 1.  Cisplatin/5-FU Yes 
   2.  Taxol/5FU  
   3.  Camptosar  
19 Lung 1.  Taxol/carbo Yes 
   2.  Navelbine  
   3.  Gemcitabine/Herceptin  
   4.  Camptosar  
   5.  Taxol  
21 Lung 1.  Taxol/Carbo Yes 
22 Melanoma 1.  Interferon Yes 
   2.  Vaccine/IL-2  
   3.  Dacarbazine  
Hematologic malignancy patients  
Lymphoma
Large cell
Follicular mixed 
1.  Cytoxan/vincristine/Adriamycin/
prednisone (CHOP)
2.  Etoposide/Solu-Medrol/ARA-C/
cisplatin (ESHAP)
3.  Cytoxan
4.  Autologous stem cell transplantation (BMT) (Cytoxan/etoposide/BCNU) 
Yes 
Lymphoma large cell 1.  CHOP
2.  ESHAP
3.  Rituxan 
Yes 
Myeloma 1.  Melphalan/prednisone
2.  Vincristine/Cytoxan/Adriamycin/
prednisone
3.  Cytoxan
4.  Auto BMT (busulfan/Cytoxan/thiotepa)
5.  Interferon
6.  Decadron/Cytoxan/etoposide/
prednisone 
Yes 
Myeloma 1.  VAD (vincristine/Adriamycin Decadron)
2.  Cytoxan
3.  Auto BMT (melphalan) 
Yes  
Chronic myelogenous leukemia 1.  Idarubicin/vincristine/prednisone
2.  Allo BMT (Cytoxan/TBI) 
Yes  
11 Lymphoma large cell 1.  CHOP
2.  Ifosfamide/carboplatin/etoposide (ICE)
3.  ESHAP
4.  CHOP 
No 
12 Lymphoma lymphoblastic 1.  CHOP
2.  Cytoxan
3.  Auto BMT (Cytoxan/BCNU/
etoposide) 
No 
14 Lymphoma large cell 1.  CHOP
2.  ESHAP
3.  ICE
4.  Rituxan
5.  Etoposide/prednisone/vincristine/
Cytoxan 
Yes 
20 Lymphoma large cell 1.  CHOP
2.  ICE
3.  Cytoxan
4.  Auto BMT (Cytoxan/BCNU/etoposide)
5.  Taxol/topotecan
6.  Rituxan 
No 
23 CLL 1.  Fludarabine-Cytoxan
2.  Solu-Medrol
3.  Adriamycin-etoposide-vincristine
4.  Chlorambucil
5.  Rituxan 
Yes 
24 Lymphoma large cell 1.  CHOP
2.  ESHAP 
Yes 
25 AML 1.  Idarubicin/ARA-C No 
   2.  Mitoxantrone/etoposide  
   3.  Daunorubicin/ARA-C  
Unique patient IDDiagnosisNo. of prior regimensChemotherapyRadiation
Solid tumor patients 
Esophageal cancer 1.  5-FU/cisplatin Yes 
Hepatocellular  No 
Neuroendocrine 1.  VP-16/cisplatin No 
   2.  Carbo/Taxol/VP-16  
Adrenocortical 1.  Mitotane Yes 
10 Sarcoma  Yes  
13 Melanoma  Yes 
15 Lung 1.  Cisplatin/etoposide No 
   2.  Topotecan  
   3.  Taxol/Carbo  
16 Pancreatic 1.  Taxol Yes 
17 Renal cell  Yes 
18 Esophageal 1.  Cisplatin/5-FU Yes 
   2.  Taxol/5FU  
   3.  Camptosar  
19 Lung 1.  Taxol/carbo Yes 
   2.  Navelbine  
   3.  Gemcitabine/Herceptin  
   4.  Camptosar  
   5.  Taxol  
21 Lung 1.  Taxol/Carbo Yes 
22 Melanoma 1.  Interferon Yes 
   2.  Vaccine/IL-2  
   3.  Dacarbazine  
Hematologic malignancy patients  
Lymphoma
Large cell
Follicular mixed 
1.  Cytoxan/vincristine/Adriamycin/
prednisone (CHOP)
2.  Etoposide/Solu-Medrol/ARA-C/
cisplatin (ESHAP)
3.  Cytoxan
4.  Autologous stem cell transplantation (BMT) (Cytoxan/etoposide/BCNU) 
Yes 
Lymphoma large cell 1.  CHOP
2.  ESHAP
3.  Rituxan 
Yes 
Myeloma 1.  Melphalan/prednisone
2.  Vincristine/Cytoxan/Adriamycin/
prednisone
3.  Cytoxan
4.  Auto BMT (busulfan/Cytoxan/thiotepa)
5.  Interferon
6.  Decadron/Cytoxan/etoposide/
prednisone 
Yes 
Myeloma 1.  VAD (vincristine/Adriamycin Decadron)
2.  Cytoxan
3.  Auto BMT (melphalan) 
Yes  
Chronic myelogenous leukemia 1.  Idarubicin/vincristine/prednisone
2.  Allo BMT (Cytoxan/TBI) 
Yes  
11 Lymphoma large cell 1.  CHOP
2.  Ifosfamide/carboplatin/etoposide (ICE)
3.  ESHAP
4.  CHOP 
No 
12 Lymphoma lymphoblastic 1.  CHOP
2.  Cytoxan
3.  Auto BMT (Cytoxan/BCNU/
etoposide) 
No 
14 Lymphoma large cell 1.  CHOP
2.  ESHAP
3.  ICE
4.  Rituxan
5.  Etoposide/prednisone/vincristine/
Cytoxan 
Yes 
20 Lymphoma large cell 1.  CHOP
2.  ICE
3.  Cytoxan
4.  Auto BMT (Cytoxan/BCNU/etoposide)
5.  Taxol/topotecan
6.  Rituxan 
No 
23 CLL 1.  Fludarabine-Cytoxan
2.  Solu-Medrol
3.  Adriamycin-etoposide-vincristine
4.  Chlorambucil
5.  Rituxan 
Yes 
24 Lymphoma large cell 1.  CHOP
2.  ESHAP 
Yes 
25 AML 1.  Idarubicin/ARA-C No 
   2.  Mitoxantrone/etoposide  
   3.  Daunorubicin/ARA-C  

5-FU indicates 5-fluorouracil; carbo, carboplatin; and IL-2, interleukin 2.

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