Table 2. Patient characteristics in... | American Society of Hematology

Table 2.

Patient characteristics in relation to numbers of active caspase 3–positive H/RS cells

Characteristic	Active caspase 3–positive H/RS cells (%)		P
Characteristic	≤ 5% (n = 41)	> 5% (n = 22)	P
Median age (y)	32.0 (14-76)	27.0 (10-71)	NS^‡
Sex
M	24	12	—
F	17	10	NS
Stage
I	6	2	—
II	22	14	—
III	4	1	—
IV	9	5	NS
B symptoms^*
Yes	22	12	—
No	15	10	NS
Therapy
Radiotherapy only	18^†	9	—
Chemotherapy	15	10	—
Chemotherapy and radiotherapy	8	3	NS
Complete remission
Yes	34	22	—
No	7	0	.04
Relapse
Yes	23	3	—
No	18	19	.001
Death
Yes	11	0	—
No	30	22	.007

Characteristic	Active caspase 3–positive H/RS cells (%)		P
Characteristic	≤ 5% (n = 41)	> 5% (n = 22)	P
Median age (y)	32.0 (14-76)	27.0 (10-71)	NS^‡
Sex
M	24	12	—
F	17	10	NS
Stage
I	6	2	—
II	22	14	—
III	4	1	—
IV	9	5	NS
B symptoms^*
Yes	22	12	—
No	15	10	NS
Therapy
Radiotherapy only	18^†	9	—
Chemotherapy	15	10	—
Chemotherapy and radiotherapy	8	3	NS
Complete remission
Yes	34	22	—
No	7	0	.04
Relapse
Yes	23	3	—
No	18	19	.001
Death
Yes	11	0	—
No	30	22	.007

P values were determined by χ² analysis, unless stated otherwise.

Data concerning the presence or absence of B symptoms could not be retrieved for 4 patients.

Seven of these patients underwent additional chemotherapy following relapse.

As determined by the Mann-Whitney U test.