MFGS-gc transduction of X-linked severe combined immunodeficiency B-cell lines
XSCID phenotype . | N* . | Appearance or increase (%) of γc on cells after transduction with MFGS-gc with envelope† . | Geometric mean channel increase‡ . | ||||
---|---|---|---|---|---|---|---|
Amphotropic . | GALV . | RD114 . | Amphotropic . | GALV . | RD114 . | ||
γ (Pt 1, 2) | 4 | 14 ± 9 | 17 ± 9 | 39 ± 16 | 167 ± 46 | 179 ± 42 | 209 ± 37 |
γ (Pt 3) | 2 | 2 ± 1 | 0 ± 0 | 13 ± 16 | 41 ± 58 | 50 ± 51 | 114 ± 13 |
XSCID phenotype . | N* . | Appearance or increase (%) of γc on cells after transduction with MFGS-gc with envelope† . | Geometric mean channel increase‡ . | ||||
---|---|---|---|---|---|---|---|
Amphotropic . | GALV . | RD114 . | Amphotropic . | GALV . | RD114 . | ||
γ (Pt 1, 2) | 4 | 14 ± 9 | 17 ± 9 | 39 ± 16 | 167 ± 46 | 179 ± 42 | 209 ± 37 |
γ (Pt 3) | 2 | 2 ± 1 | 0 ± 0 | 13 ± 16 | 41 ± 58 | 50 ± 51 | 114 ± 13 |