FACS analysis of CD45RA subset composition in thymomas of MG(+) and MG(−) patients, gated on CD3+ T cells
Patient . | Case number . | WHO thymoma subtype . | MG . | CD4-CD8 ratio . | CD45RA+cells, % CD3 . | % CD45RA+ CD3+ . | |
---|---|---|---|---|---|---|---|
CD4 . | CD8 . | ||||||
1 | 94/24 864 | AB | Yes | 0.24 | 26.0 | 10.6 | 15.4 |
2 | 98/5 633 | AB | Yes | 1.8 | 32.6 | 10.0 | 22.6 |
3 | 99/13 575 | B2 | Yes | 1.2 | 52.0 | 26.7 | 25.3 |
4 | 95/1 064 | B2 | Yes | 1.2 | 52.1 | 24.4 | 27.7 |
5 | 00/25 907 | B2 | Yes | 0.58 | 41.7 | 27.1 | 14.6 |
6 | 00/22 717 | B2 | Yes | 0.57 | 48.8 | 12.1 | 36.8 |
7 | 00/20 223 | B2 of B3 | Yes | 0.79 | 93.7 | 71.4 | 22.3 |
8 | 99/21 994 | B2 | Yes | 3.0 | 74.5 | 22.7 | 51.7 |
9 | 99/3 983 | B2 | Yes | 4.2 | 21.7 | 14.6 | 7.1 |
Average, patients 1-9 | 1.51 | 49.2 ± 23.1 | 24.4 ± 18.9 | 24.8 ± 13.2 | |||
10 | 95/15 091 | AB | No | 0.5 | 6.8 | 2.5 | 4.5 |
11 | 00/21 586 | AB | No | 0.3 | 46.9 | 5.6 | 41.4 |
12 | 95/12 211 | AB | No | 0.16 | 8.9 | 2.9 | 6.0 |
13 | 00/1 495 | AB | No | 0.11 | 12.7 | 2.7 | 10.0 |
14 | 01/4 054 | AB | No | 0.18 | 18.9 | 4.2 | 14.7 |
15 | 01/261 | AB | No | 0.26 | 24.0 | 3.7 | 20.7 |
16 | 93/23 169 | B2 | No | 0.45 | 16.1 | 4.5 | 11.6 |
17 | 00/3 045 | B2 | No | 1.8 | 17.6 | 9.8 | 7.8 |
18 | 97/6 635 | B2 | No | 0.06 | 46.9 | 2.4 | 44.5 |
19 | 01/5 447 | B2 | No | 0.26 | 27.0 | 5.2 | 22.1 |
20 | 98/5 186 | B2 + B3 | No | 0.12 | 13.2 | 3.1 | 10.1 |
21 | 01/6 600 | B2 + B3 | No | 0.25 | 14.1 | 4.3 | 9.9 |
22 | 97/20 308 | B2 + B3 | No | 0.16 | 41.4 | 5.1 | 36.3 |
Average, patients 10-22 | 0.35 | 20.1 ± 15.2 | 4.3 ± 2.0 | 18.4 ± 13.7 | |||
23-35 thymus controls | TFH | Yes | 1.0-3.3 | 17.6-55.6 | 8.1-32.8 | 9.5-22.2 | |
Average, patients 23-35 thymus controls | 2.5 | 33.7 ± 12.7 | 19.1 ± 10.6 | 12.9 ± 3.9 |
Patient . | Case number . | WHO thymoma subtype . | MG . | CD4-CD8 ratio . | CD45RA+cells, % CD3 . | % CD45RA+ CD3+ . | |
---|---|---|---|---|---|---|---|
CD4 . | CD8 . | ||||||
1 | 94/24 864 | AB | Yes | 0.24 | 26.0 | 10.6 | 15.4 |
2 | 98/5 633 | AB | Yes | 1.8 | 32.6 | 10.0 | 22.6 |
3 | 99/13 575 | B2 | Yes | 1.2 | 52.0 | 26.7 | 25.3 |
4 | 95/1 064 | B2 | Yes | 1.2 | 52.1 | 24.4 | 27.7 |
5 | 00/25 907 | B2 | Yes | 0.58 | 41.7 | 27.1 | 14.6 |
6 | 00/22 717 | B2 | Yes | 0.57 | 48.8 | 12.1 | 36.8 |
7 | 00/20 223 | B2 of B3 | Yes | 0.79 | 93.7 | 71.4 | 22.3 |
8 | 99/21 994 | B2 | Yes | 3.0 | 74.5 | 22.7 | 51.7 |
9 | 99/3 983 | B2 | Yes | 4.2 | 21.7 | 14.6 | 7.1 |
Average, patients 1-9 | 1.51 | 49.2 ± 23.1 | 24.4 ± 18.9 | 24.8 ± 13.2 | |||
10 | 95/15 091 | AB | No | 0.5 | 6.8 | 2.5 | 4.5 |
11 | 00/21 586 | AB | No | 0.3 | 46.9 | 5.6 | 41.4 |
12 | 95/12 211 | AB | No | 0.16 | 8.9 | 2.9 | 6.0 |
13 | 00/1 495 | AB | No | 0.11 | 12.7 | 2.7 | 10.0 |
14 | 01/4 054 | AB | No | 0.18 | 18.9 | 4.2 | 14.7 |
15 | 01/261 | AB | No | 0.26 | 24.0 | 3.7 | 20.7 |
16 | 93/23 169 | B2 | No | 0.45 | 16.1 | 4.5 | 11.6 |
17 | 00/3 045 | B2 | No | 1.8 | 17.6 | 9.8 | 7.8 |
18 | 97/6 635 | B2 | No | 0.06 | 46.9 | 2.4 | 44.5 |
19 | 01/5 447 | B2 | No | 0.26 | 27.0 | 5.2 | 22.1 |
20 | 98/5 186 | B2 + B3 | No | 0.12 | 13.2 | 3.1 | 10.1 |
21 | 01/6 600 | B2 + B3 | No | 0.25 | 14.1 | 4.3 | 9.9 |
22 | 97/20 308 | B2 + B3 | No | 0.16 | 41.4 | 5.1 | 36.3 |
Average, patients 10-22 | 0.35 | 20.1 ± 15.2 | 4.3 ± 2.0 | 18.4 ± 13.7 | |||
23-35 thymus controls | TFH | Yes | 1.0-3.3 | 17.6-55.6 | 8.1-32.8 | 9.5-22.2 | |
Average, patients 23-35 thymus controls | 2.5 | 33.7 ± 12.7 | 19.1 ± 10.6 | 12.9 ± 3.9 |