Number of different types of CFCs detected before and after transduction of CD34+CD45RA+CD71−(granulopoietic) CB cells with MIG or p210 in the presence of FL, G-CSF, and GM-CSF
Progenitor . | Before transduction3-150 . | After MIG3-150 . | After p2103-150 . |
---|---|---|---|
CFU-E | 0, ND | 0, 0 | 2, 3 |
BFU-E | 0, ND | 0, 0 | 9, 5 |
CFU-GEMM | 0, ND | 0, 0 | 0, 0 |
CFU-GM | 12, ND | 84, 107 | 41, 51 |
Total CFC | 12, ND | 84, 107 | 52, 59 |
Progenitor . | Before transduction3-150 . | After MIG3-150 . | After p2103-150 . |
---|---|---|---|
CFU-E | 0, ND | 0, 0 | 2, 3 |
BFU-E | 0, ND | 0, 0 | 9, 5 |
CFU-GEMM | 0, ND | 0, 0 | 0, 0 |
CFU-GM | 12, ND | 84, 107 | 41, 51 |
Total CFC | 12, ND | 84, 107 | 52, 59 |
ND indicates not done.
CFC numbers were calculated as described in the footnote to Table 1. Values shown are from 2 independent experiments.