Table 1. Effect of various inhibitors on... | American Society of Hematology

Table 1.

Effect of various inhibitors on mPILSAP activity

Inhibitor	Concentration (μM)	Activity (%)
None		100
Bestatin	1	84.3 ± 5.2^*
	10	66.9 ± 4.3^†
Amastatin	1	85.0 ± 6.3
	10	58.1 ± 3.4^†
Leucinethiol	1	60.0 ± 1.6^†
	10	17.4 ± 2.2^†
Fumagillin	1	79.5 ± 5.4^*
	10	60.1 ± 5.5^†
Puromycin	10	97.5 ± 3.8
1,10-Phenanthroline	10	92.6 ± 5.4
ZnCl₂	10	27.8 ± 4.9^†
Leupeptin	10	94.8 ± 2.9
Aprotinin	10	100.9 ± 3.7
Pepstatin	10	95.5 ± 5.0

Inhibitor	Concentration (μM)	Activity (%)
None		100
Bestatin	1	84.3 ± 5.2^*
	10	66.9 ± 4.3^†
Amastatin	1	85.0 ± 6.3
	10	58.1 ± 3.4^†
Leucinethiol	1	60.0 ± 1.6^†
	10	17.4 ± 2.2^†
Fumagillin	1	79.5 ± 5.4^*
	10	60.1 ± 5.5^†
Puromycin	10	97.5 ± 3.8
1,10-Phenanthroline	10	92.6 ± 5.4
ZnCl₂	10	27.8 ± 4.9^†
Leupeptin	10	94.8 ± 2.9
Aprotinin	10	100.9 ± 3.7
Pepstatin	10	95.5 ± 5.0

P < .05 versus control.

P < .005 versus control.