Cytogenetic subgroup comparisons: estimates and confidence intervals
| . | With trisomy 8 . | Without trisomy 8 . | P . | ||||
|---|---|---|---|---|---|---|---|
| Estimate (%) . | 95% CI . | N . | Estimate (%) . | 95% CI . | N . | ||
| Complete response (%) | |||||||
| Favorable | 77 | 55-92 | 22 | 66 | 58-74 | 149 | .31 |
| Intermediate | 58 | 43-72 | 50 | 53 | 47-58 | 333 | .50 |
| Unfavorable | 23 | 10-40 | 35 | 40 | 34-47 | 235 | .051 |
| Probability of surviving 2 y | |||||||
| Favorable | 48 | 27-69 | 23 | 57 | 49-65 | 153 | .80 |
| Intermediate | 23 | 11-35 | 50 | 34 | 29-40 | 333 | .12 |
| Unfavorable | 6 | 0-14 | 35 | 13 | 9-17 | 235 | .0096 |
| . | With trisomy 8 . | Without trisomy 8 . | P . | ||||
|---|---|---|---|---|---|---|---|
| Estimate (%) . | 95% CI . | N . | Estimate (%) . | 95% CI . | N . | ||
| Complete response (%) | |||||||
| Favorable | 77 | 55-92 | 22 | 66 | 58-74 | 149 | .31 |
| Intermediate | 58 | 43-72 | 50 | 53 | 47-58 | 333 | .50 |
| Unfavorable | 23 | 10-40 | 35 | 40 | 34-47 | 235 | .051 |
| Probability of surviving 2 y | |||||||
| Favorable | 48 | 27-69 | 23 | 57 | 49-65 | 153 | .80 |
| Intermediate | 23 | 11-35 | 50 | 34 | 29-40 | 333 | .12 |
| Unfavorable | 6 | 0-14 | 35 | 13 | 9-17 | 235 | .0096 |
Comparisons that reached statistical significance in any of the risk group categories are included regardless of whether the risk group/+ 8 interaction was statistically significant. The log-rank statistic was used to test significance for the OS comparisons.
The median for the favorable risk group in Table 5 was not meaningful because the medians are only just reached in that group. Therefore, 2-year survival rates rather than medians are used for all risk groups to be consistent.