Prior therapies and response of 16 patients with relapsed mantle cell lymphoma treated with I-131-Tositumomab, etoposide, cyclophosphamide, and autologous stem cell transplantation
| Patient no. . | Prior therapies, no. of cycles, and response . |
|---|---|
| 1 | CHOP × 4→PR; CED × 1→NR |
| 2 | CVP × 5→UR; splenectomy; Flu × 5→NR; CHOP × 2→PR |
| 3 | CY × 6→PR; CED × 1→NR |
| 4 | COP × 6→NR; CY/Pred × 1→NR |
| 5 | CHOP + R × 6→CR; ESHAP × 3→PR |
| 6 | CHOP × 6→PR; ESHAP × 1→UR; DHAP × 1/CY × 1→PR; splenectomy |
| 7 | CHOP × 8→PR, CVP × 1→PR, R × 8→PR |
| 8 | CHOP × 6→CR, CY × 1→PR |
| 9 | CHOP × 6→PR, CVP × 5→NR, R→NR |
| 10 | CHOP × 6/R × 4→CR, R × 6→CR, R × 6→NR, CED × 1→PR |
| 11 | CHOP × 6→PR, CED→NR |
| 12 | CHOP+ R × 6→CR; Dex→NR; DHAP × 2→PD; R × 4/XRT→PR; CED→PR |
| 13 | CHOP × 6→PR; R × 4→PR; CED × 1→NR |
| 14 | CHOP+ R→PR; R→NR; CVP × 3→PR; ESHAP × 2→NR; CED × 1→PR |
| 15 | CHOP+ R→CR; DHAP × 1→PR; CY/Dex→PR |
| 16 | CHOP × 6→PR; CED/R→NR |
| Patient no. . | Prior therapies, no. of cycles, and response . |
|---|---|
| 1 | CHOP × 4→PR; CED × 1→NR |
| 2 | CVP × 5→UR; splenectomy; Flu × 5→NR; CHOP × 2→PR |
| 3 | CY × 6→PR; CED × 1→NR |
| 4 | COP × 6→NR; CY/Pred × 1→NR |
| 5 | CHOP + R × 6→CR; ESHAP × 3→PR |
| 6 | CHOP × 6→PR; ESHAP × 1→UR; DHAP × 1/CY × 1→PR; splenectomy |
| 7 | CHOP × 8→PR, CVP × 1→PR, R × 8→PR |
| 8 | CHOP × 6→CR, CY × 1→PR |
| 9 | CHOP × 6→PR, CVP × 5→NR, R→NR |
| 10 | CHOP × 6/R × 4→CR, R × 6→CR, R × 6→NR, CED × 1→PR |
| 11 | CHOP × 6→PR, CED→NR |
| 12 | CHOP+ R × 6→CR; Dex→NR; DHAP × 2→PD; R × 4/XRT→PR; CED→PR |
| 13 | CHOP × 6→PR; R × 4→PR; CED × 1→NR |
| 14 | CHOP+ R→PR; R→NR; CVP × 3→PR; ESHAP × 2→NR; CED × 1→PR |
| 15 | CHOP+ R→CR; DHAP × 1→PR; CY/Dex→PR |
| 16 | CHOP × 6→PR; CED/R→NR |
CHOP indicates cyclophosphamide, doxorubicin, vincristine, prednisone; PR, partial response; CED, cyclophosphamide, etoposide, dexamethasone; NR, no response; CVP, cyclophosphamide, vincristine, prednisone; UR, unknown response; Flu, fludarabine; CY, cyclophosphamide; COP, cyclophosphamide, vincristine, prednisone; Pred, prednisone; R, rituximab; CR, complete response; ESHAP, etoposide, methylprednisolone, cytarabine, cisplatin; DHAP, dexamethasone, cytarabine, cisplatin; Dex, dexamethasone; and XRT, radiation therapy.