Frequency of Chk2, p53, and p16alterations in primary hematopoietic neoplasms
| Diagnosis . | No. of patients . | No. of mutations . | ||
|---|---|---|---|---|
| Chk2 . | p53 . | p16 . | ||
| ALL | 14 | 0 | 0 | 5 |
| AML | 55 | 1 | 5 | 1 |
| CML | 12 | 0 | 0 | 0 |
| CLL | 5 | 0 | 1 | 1 |
| PLL | 2 | 0 | 1 | 0 |
| NHL | 7 | 1 | 0 | 1 |
| ATL | 4 | 0 | 0 | 1 |
| MM | 2 | 0 | 0 | 0 |
| MDS | 8 | 0 | 0 | 0 |
| Total | 109 | 2 | 7 | 9 |
| Diagnosis . | No. of patients . | No. of mutations . | ||
|---|---|---|---|---|
| Chk2 . | p53 . | p16 . | ||
| ALL | 14 | 0 | 0 | 5 |
| AML | 55 | 1 | 5 | 1 |
| CML | 12 | 0 | 0 | 0 |
| CLL | 5 | 0 | 1 | 1 |
| PLL | 2 | 0 | 1 | 0 |
| NHL | 7 | 1 | 0 | 1 |
| ATL | 4 | 0 | 0 | 1 |
| MM | 2 | 0 | 0 | 0 |
| MDS | 8 | 0 | 0 | 0 |
| Total | 109 | 2 | 7 | 9 |
ALL indicates acute lymphocytic leukemia; AML, acute myelocytic leukemia; CML, chronic myelocytic leukemia; CLL, chronic lymphocytic leukemia; PLL, prolymphocytic leukemia; NHL, non-Hodgkin lymphoma; ATL, adult T-cell lymphoma/leukemia; MM, multiple myeloma; MDS, myelodysplastic syndrome.