Toxicity of EPOCH chemotherapy in 50 patients
| Variable . | Value . |
|---|---|
| No. (%) of cycles | 318 (100) |
| Hospitalization | |
| No. (%) cycles with hospitalization for fever and neutropenia | 26 (8) |
| No. (%) cycles with hospitalization for other reason | 15 (5) |
| Hematologic toxicity | |
| No. (%) cycles with ANC less than 0.1 × 109/L | 47 (15) |
| No. (%) cycles with ANC 0.1 to 0.5 × 109/L | 109 (34) |
| No. (%) cycles with platelet count less than 25 × 109/L | 21 (7) |
| No. (%) cycles with platelet count 26 to 50 × 109/L | 40 (13) |
| Toxicity at least grade 25-150 | |
| Gastrointestinal | |
| No. (%) cycles with nausea or vomiting | 19 (6) |
| No. (%) cycles with stomatitis | 39 (12) |
| No. (%) cycles with constipation | 13 (4) |
| Neurologic | |
| No. (%) patients with sensory effects | 14 (28) |
| No. (%) patients with motor effects | 6 (12) |
| No. (%) patients with fatigue | 13 (26) |
| No. (%) patients with cardiac effects | 0 (0) |
| No. (%) of treatment-related deaths | 0 (0) |
| Variable . | Value . |
|---|---|
| No. (%) of cycles | 318 (100) |
| Hospitalization | |
| No. (%) cycles with hospitalization for fever and neutropenia | 26 (8) |
| No. (%) cycles with hospitalization for other reason | 15 (5) |
| Hematologic toxicity | |
| No. (%) cycles with ANC less than 0.1 × 109/L | 47 (15) |
| No. (%) cycles with ANC 0.1 to 0.5 × 109/L | 109 (34) |
| No. (%) cycles with platelet count less than 25 × 109/L | 21 (7) |
| No. (%) cycles with platelet count 26 to 50 × 109/L | 40 (13) |
| Toxicity at least grade 25-150 | |
| Gastrointestinal | |
| No. (%) cycles with nausea or vomiting | 19 (6) |
| No. (%) cycles with stomatitis | 39 (12) |
| No. (%) cycles with constipation | 13 (4) |
| Neurologic | |
| No. (%) patients with sensory effects | 14 (28) |
| No. (%) patients with motor effects | 6 (12) |
| No. (%) patients with fatigue | 13 (26) |
| No. (%) patients with cardiac effects | 0 (0) |
| No. (%) of treatment-related deaths | 0 (0) |
ANC indicates absolute neutrophil count.
According to the National Cancer Institute's common toxicity criteria.