Table 1.

Chromosomal instability of wildtype and G3 in Terc−/− C57BL6 bone marrow cells 5 months after primary transplantation

Transplanted cellsMetaphases analyzed, no.Translocations foundCells with translocations, %
Wildtype (XY) 25 t(16;?), in 1 metaphase 4  
G3 mTerc−/− B6 (XY) 27 t(5;6), in 8 metaphases 36* 
  t(7;13), in 1 metaphase  
Transplanted cellsMetaphases analyzed, no.Translocations foundCells with translocations, %
Wildtype (XY) 25 t(16;?), in 1 metaphase 4  
G3 mTerc−/− B6 (XY) 27 t(5;6), in 8 metaphases 36* 
  t(7;13), in 1 metaphase  

mTerc indicates telomerase-deficient mice; B6 indicates C57BL6.

*

P < .01.

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