Table 4.

Comparison of clinical features of trisomy 8 and monosomy 7

AbnormalityP
−74-154+8
114-150  
Age (y) 41 ± 24 42 ± 12 .87 
Time to evolution (mo) 47 ± 36 28 ± 25 .21 
Mortality (%) 50% 0% .0894-151 
Initial blood counts    
 ANC × 103/μL 425 ± 250 811 ± 354 .0152 
 Hemoglobin (g/dL) 7.2 ± 2.6 8 ± 1.7 .48 
 Reticulocytes × 103/μL 18 ± 18 21 ± 12 .67 
 Platelets × 103/μL 12 ± 5 18 ± 11 .11  
Blood counts at evolution    
 ANC × 103/μL 489 ± 217 2085 ± 768 .0001 
 Hemoglobin (g/dL) 8.8 ± 1.8 11.4 ± 2.2 .0169 
 Reticulocytes × 103/μL 29 ± 18 58 ± 23 .0114 
 Platelets × 103/μL 40 ± 50 86 ± 49 .07 
Response of AA to IST (%) 25% 100% .0134-151 
AbnormalityP
−74-154+8
114-150  
Age (y) 41 ± 24 42 ± 12 .87 
Time to evolution (mo) 47 ± 36 28 ± 25 .21 
Mortality (%) 50% 0% .0894-151 
Initial blood counts    
 ANC × 103/μL 425 ± 250 811 ± 354 .0152 
 Hemoglobin (g/dL) 7.2 ± 2.6 8 ± 1.7 .48 
 Reticulocytes × 103/μL 18 ± 18 21 ± 12 .67 
 Platelets × 103/μL 12 ± 5 18 ± 11 .11  
Blood counts at evolution    
 ANC × 103/μL 489 ± 217 2085 ± 768 .0001 
 Hemoglobin (g/dL) 8.8 ± 1.8 11.4 ± 2.2 .0169 
 Reticulocytes × 103/μL 29 ± 18 58 ± 23 .0114 
 Platelets × 103/μL 40 ± 50 86 ± 49 .07 
Response of AA to IST (%) 25% 100% .0134-151 

Statistical analysis: t test (normal distribution) or Wilcoxon test when appropriate.

F4-150

Patient with a transient abnormality not included.

F4-151

χ2 test.

F4-154

Numerical and structural abnormalities.

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