Comparison of adverse events in high-dose and low-dose prednisone maintenance
| Toxicity . | Number of events grade 3 or higher4-150 . | |
|---|---|---|
| Prednisone, 10 mg (n = 61) . | Prednisone, 50 mg (n = 51) . | |
| Infections | 1 (0) | 2 (1) |
| Edema | 2 (0) | 8 (2) |
| Weight gain | 1 (0) | 0 |
| Personality changes | 0 | 4 (0) |
| Muscle weakness | 7 (1) | 4 (0) |
| Myalgias | 3 (0) | 2 (1) |
| Cushingoid appearance | 0 | 6 (0) |
| Toxicity . | Number of events grade 3 or higher4-150 . | |
|---|---|---|
| Prednisone, 10 mg (n = 61) . | Prednisone, 50 mg (n = 51) . | |
| Infections | 1 (0) | 2 (1) |
| Edema | 2 (0) | 8 (2) |
| Weight gain | 1 (0) | 0 |
| Personality changes | 0 | 4 (0) |
| Muscle weakness | 7 (1) | 4 (0) |
| Myalgias | 3 (0) | 2 (1) |
| Cushingoid appearance | 0 | 6 (0) |
Note that 13 patients on each arm experienced toxicities of grade 3 or higher as their worst degree of toxicity. Some patients had multiple toxicities of grade 3 or higher.