Table 1.

Characteristics of the study population

Blood cell parametersSubjects*
African controls (n = 11)Non-VOC group (n = 15)VOC group (n = 17)HU group (n = 9)
Leukocytes 4.40 ± 0.29 12.50 ± 0.551-155 13.47 ± 1.101-155 10.12 ± 0.671-155,1-154 
PMNs 2.15 ± 0.24 6.13 ± 0.391-155 6.08 ± 0.511-155 5.05 ± 0.541-155 
Monocytes 0.30 ± 0.01 1.07 ± 0.021-155 0.92 ± 0.011-155 0.88 ± 0.011-155 
Platelets 266 ± 18 440 ± 291-155 444 ± 311-155 386 ± 291-155 
Hb 124 ± 3 80 ± 21-155 75 ± 21-155 82 ± 41-155 
HbF1-153 — 11.2 ± 1.4 8.3 ± 1.11-159 12.4 ± 1.9 
Blood cell parametersSubjects*
African controls (n = 11)Non-VOC group (n = 15)VOC group (n = 17)HU group (n = 9)
Leukocytes 4.40 ± 0.29 12.50 ± 0.551-155 13.47 ± 1.101-155 10.12 ± 0.671-155,1-154 
PMNs 2.15 ± 0.24 6.13 ± 0.391-155 6.08 ± 0.511-155 5.05 ± 0.541-155 
Monocytes 0.30 ± 0.01 1.07 ± 0.021-155 0.92 ± 0.011-155 0.88 ± 0.011-155 
Platelets 266 ± 18 440 ± 291-155 444 ± 311-155 386 ± 291-155 
Hb 124 ± 3 80 ± 21-155 75 ± 21-155 82 ± 41-155 
HbF1-153 — 11.2 ± 1.4 8.3 ± 1.11-159 12.4 ± 1.9 
*

Subjects described in “Patients, materials, and methods.”

Means ± SEM blood cell counts, × 109/L.

Means ± SEM of Hb values, g/L.

F1-153

Means ± SEM of HbF, %.

F1-155

Significantly different from controls (P< .05).

F1-154

Significantly different from the other patient groups (P < .05).

F1-159

Significantly different from HU-treated patients (P < .05).

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