Results of Cox proportional hazard analysis of HBV virologic factors predictive of hepatitis due to HBV reactivation in HBsAg-positive patients after autologous hematopoietic cell transplantation
Variable . | Hazard ratio4-150 . | 95% CI . | P4-151 . |
---|---|---|---|
HBV DNA‡ | |||
Detectable | 9.35 | 1.65-52.6 | .012 |
Undetectable | 1 | ||
Genotype | |||
C | 1.47 | 0.16-13.50 | .734 |
B | 1 | ||
BCP | |||
Positive | 2.02 | 0.70-43.48 | .448 |
Negative | 1 | ||
Pretransplantation ALT | |||
Elevated | 5.49 | 0.07-6.25 | .105 |
Normal | 1 |
Variable . | Hazard ratio4-150 . | 95% CI . | P4-151 . |
---|---|---|---|
HBV DNA‡ | |||
Detectable | 9.35 | 1.65-52.6 | .012 |
Undetectable | 1 | ||
Genotype | |||
C | 1.47 | 0.16-13.50 | .734 |
B | 1 | ||
BCP | |||
Positive | 2.02 | 0.70-43.48 | .448 |
Negative | 1 | ||
Pretransplantation ALT | |||
Elevated | 5.49 | 0.07-6.25 | .105 |
Normal | 1 |
CI indicates confidence interval. For explanation of other abbreviations, see Table 1.
Hazard ratios above 1.00 represent an increased risk of hepatitis due to HBV reactivation; those below 1.00 represent a decreased risk of hepatitis due to HBV reactivation.
Based on the hypothesis that the hazard ratio determined by a Cox proportional hazards analysis is equal to 1.0.
On Digene Hybrid Capture II assay.